Download MendeleyCrystal structure of the human mineralocorticoid receptor ligand-binding domain bound to deoxycorticosterone
Huyet, J., Pinon, G.-M., Rochel, M., Mayer, C., Rafestin-Oblin, M.-E., Fagart, J.To be published.
2ABI
Crystal structure of the human mineralocorticoid receptor ligand-binding domain bound to deoxycorticosterone
- PDB DOI: https://doi.org/10.2210/pdb2ABI/pdb
- Classification: TRANSCRIPTION REGULATOR
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): Yes
- Deposited: 2005-07-15 Released: 2006-07-25
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.33 ?
- R-Value Free: 0.264
- R-Value Work: 0.207
- R-Value Observed: 0.207
Starting Model: experimental
View more details
This is version 1.4 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Mineralocorticoid receptor | 256 | Homo sapiens | Mutation(s): 1 Gene Names: NR3C2, MCR, MLR |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P08235 (Homo sapiens) Explore P08235 Go to UniProtKB: P08235 | |||||
PHAROS: P08235 GTEx: ENSG00000151623 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P08235 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| 1CA Query on 1CA | D [auth A], E [auth B], F [auth C] | DESOXYCORTICOSTERONE C21 H30 O3 ZESRJSPZRDMNHY-YFWFAHHUSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.33 ?
- R-Value Free: 0.264
- R-Value Work: 0.207
- R-Value Observed: 0.207
- Space Group: P 31
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 119.77 | ¦Á = 90 |
| b = 119.77 | ¦Â = 90 |
| c = 41.5 | ¦Ă = 120 |
| Software Name | Purpose |
|---|---|
| XDS | data scaling |
| XDS | data reduction |
| BEAST | model building |
| CNS | refinement |
| BEAST | phasing |
Entry History
Deposition Data
- Released Date: 2006-07-25 Deposition Author(s): Huyet, J., Pinon, G.-M., Rochel, M., Mayer, C., Rafestin-Oblin, M.-E., Fagart, J.
Revision History (Full details and data files)
- Version 1.0: 2006-07-25
Type: Initial release - Version 1.1: 2008-04-30
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Version format compliance - Version 1.3: 2021-11-10
Changes: Database references, Derived calculations - Version 1.4: 2023-10-25
Changes: Data collection, Refinement description
