Download MendeleySubstrates and Inhibitors of the Fluorinase from Streptomyces Cattleya
McEwan, A.R., Deng, H., Mcglinchey, R.P., Robinson, D.R., O'Hagan, D., Naismith, J.H.To be published.
2C4T
X-ray crystal structure of 5'-fluorodeoxyadenosine synthase from Streptomyces cattleya complexed with an inhibitor, an analogue of S- adenosyl methionine
- PDB DOI: https://doi.org/10.2210/pdb2C4T/pdb
- Classification: TRANSFERASE
- Organism(s): Streptantibioticus cattleyicolor
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2005-10-22 Released: 2007-03-27
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.30 ?
- R-Value Free: 0.239 (Depositor), 0.230 (DCC)
- R-Value Work: 0.184 (Depositor), 0.180 (DCC)
- R-Value Observed: 0.187 (Depositor)
Starting Model: experimental
View more details
This is version 1.4 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| 5'-FLUORO-5'-DEOXYADENOSINE SYNTHASE | 299 | Streptantibioticus cattleyicolor | Mutation(s): 0 EC: 2.5.1.63 |  | |
UniProt | |||||
Find proteins for Q70GK9 (Streptantibioticus cattleyicolor) Explore Q70GK9 Go to UniProtKB: Q70GK9 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q70GK9 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| SA8 Query on SA8 | D [auth A], I [auth C], J [auth C] | S-5'-AZAMETHIONINE-5'-DEOXYADENOSINE C15 H23 N7 O5 JISVTSUBJCPLSV-TWBCTODHSA-N |  | ||
| CL Query on CL | E [auth A] F [auth A] G [auth A] H [auth B] K [auth C] | CHLORIDE ION Cl VEXZGXHMUGYJMC-UHFFFAOYSA-M |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.30 ?
- R-Value Free: 0.239 (Depositor), 0.230 (DCC)
- R-Value Work: 0.184 (Depositor), 0.180 (DCC)
- R-Value Observed: 0.187 (Depositor)
Space Group: C 2 2 21
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 76.319 | ¦Á = 90 |
| b = 129.505 | ¦Â = 90 |
| c = 182.845 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| MOSFLM | data reduction |
| SCALA | data scaling |
| MOLREP | phasing |
Entry History
Deposition Data
- Released Date: 2007-03-27 Deposition Author(s): McEwan, A.R., Deng, H., McGlinchey, R.P., Robinson, D.R., O'Hagan, D., Naismith, J.H.
Revision History (Full details and data files)
- Version 1.0: 2007-03-27
Type: Initial release - Version 1.1: 2011-07-13
Changes: Advisory, Version format compliance - Version 1.2: 2017-06-28
Changes: Data collection - Version 1.3: 2018-03-28
Changes: Database references, Source and taxonomy - Version 1.4: 2023-12-13
Changes: Data collection, Database references, Other, Refinement description
