Download MendeleyThe Structure of Torpedo Californica Acetylcholinesterase Complexed with 2-Pam
Harel, M., Silman, I., Sussman, J.L.To be published.
2VQ6
Torpedo californica acetylcholinesterase complexed with 2-PAM
- PDB DOI: https://doi.org/10.2210/pdb2VQ6/pdb
- Entry: 2VQ6 supersedes: 2VB4
- Classification: HYDROLASE
- Organism(s): Tetronarce californica
- Mutation(s): No
- Deposited: 2008-03-11 Released: 2008-05-13
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.71 ?
- R-Value Free: 0.234
- R-Value Work: 0.171
- R-Value Observed: 0.174
Starting Model: experimental
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This is version 1.5 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| ACETYLCHOLINESTERASE | 543 | Tetronarce californica | Mutation(s): 0 EC: 3.1.1.7 |  | |
UniProt | |||||
Find proteins for P04058 (Tetronarce californica) Explore P04058 Go to UniProtKB: P04058 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P04058 | ||||
Glycosylation | |||||
| Glycosylation Sites: 2 | |||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 3 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| NAG Query on NAG | D [auth A], E [auth A] | 2-acetamido-2-deoxy-beta-D-glucopyranose C8 H15 N O6 OVRNDRQMDRJTHS-FMDGEEDCSA-N |  | ||
| FP1 Query on FP1 | B [auth A] | N-hydroxy-1-(1-methylpyridin-2(1H)-ylidene)methanamine C7 H10 N2 O YDWKOUCMHAMECR-SREVYHEPSA-N |  | ||
| SO4 Query on SO4 | C [auth A] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.71 ?
- R-Value Free: 0.234
- R-Value Work: 0.171
- R-Value Observed: 0.174
- Space Group: P 31 2 1
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 113.95 | ¦Á = 90 |
| b = 113.95 | ¦Â = 90 |
| c = 138.05 | ¦Ă = 120 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| DENZO | data reduction |
| SCALEPACK | data scaling |
| PROTIN | phasing |
Entry History
Deposition Data
- Released Date: 2008-05-13 Deposition Author(s): Harel, M., Silman, I., Sussman, J.L.
- This entry supersedes: 2VB4
Revision History (Full details and data files)
- Version 1.0: 2008-05-13
Type: Initial release - Version 1.1: 2011-05-08
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Version format compliance - Version 1.3: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Advisory, Data collection, Derived calculations, Other, Structure summary - Version 1.4: 2023-12-13
Changes: Data collection, Database references, Refinement description, Structure summary - Version 1.5: 2024-10-23
Changes: Structure summary
