Download MendeleyTetr(D) in Complex with Minocycline.
Dalm, D., Palm, G.J., Proft, J., Hinrichs, W.To be published.
2XPV
TetR(D) in complex with minocycline and magnesium.
- PDB DOI: https://doi.org/10.2210/pdb2XPV/pdb
- Classification: TRANSCRIPTION
- Organism(s): Escherichia coli
- Expression System: Escherichia coli K-12
- Mutation(s): No
- Deposited: 2010-08-30 Released: 2011-09-07
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.49 ?
- R-Value Free: 0.201
- R-Value Work: 0.185
- R-Value Observed: 0.186
Starting Model: experimental
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This is version 1.3 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| TETRACYCLINE REPRESSOR PROTEIN CLASS D | 207 | Escherichia coli | Mutation(s): 0 |  | |
UniProt | |||||
Find proteins for P0ACT4 (Escherichia coli) Explore P0ACT4 Go to UniProtKB: P0ACT4 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P0ACT4 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 3 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| MIY Query on MIY | B [auth A] | (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-
CARBOXAMIDE C23 H27 N3 O7 DYKFCLLONBREIL-KVUCHLLUSA-N |  | ||
| CL Query on CL | D [auth A] E [auth A] F [auth A] G [auth A] H [auth A] | CHLORIDE ION Cl VEXZGXHMUGYJMC-UHFFFAOYSA-M |  | ||
| MG Query on MG | C [auth A] | MAGNESIUM ION Mg JLVVSXFLKOJNIY-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.49 ?
- R-Value Free: 0.201
- R-Value Work: 0.185
- R-Value Observed: 0.186
- Space Group: I 41 2 2
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 68.686 | ¦Á = 90 |
| b = 68.686 | ¦Â = 90 |
| c = 178.673 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| HKL-2000 | data reduction |
| SCALEPACK | data scaling |
| REFMAC | phasing |
Entry History
Deposition Data
- Released Date: 2011-09-07 Deposition Author(s): Dalm, D., Proft, J., Palm, G.J., Hinrichs, W.
Revision History (Full details and data files)
- Version 1.0: 2011-09-07
Type: Initial release - Version 1.1: 2011-09-21
Changes: Atomic model - Version 1.2: 2019-07-24
Changes: Data collection, Derived calculations - Version 1.3: 2023-12-20
Changes: Data collection, Database references, Derived calculations, Other, Refinement description, Structure summary
