Download MendeleyCrystal structure of sterile 20-like kinase 3 (MST3, STK24) in complex with staurosporine.
Antonysamy, S.S., Burley, S.K., Buchanan, S., Chau, F., Feil, I., Wu, L., Sauder, J.M.To be published.
3CKX
Crystal structure of sterile 20-like kinase 3 (MST3, STK24) in complex with staurosporine
- PDB DOI: https://doi.org/10.2210/pdb3CKX/pdb
- Classification: TRANSFERASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2008-03-17 Released: 2008-04-29
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.70 ?
- R-Value Free: 0.268
- R-Value Work: 0.204
- R-Value Observed: 0.204
Starting Model: experimental
View more details
This is version 1.6 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Serine/threonine-protein kinase 24 | 304 | Homo sapiens | Mutation(s): 0 Gene Names: STK24, MST3, STK3 EC: 2.7.11.1 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q9Y6E0 (Homo sapiens) Explore Q9Y6E0 Go to UniProtKB: Q9Y6E0 | |||||
PHAROS: Q9Y6E0 GTEx: ENSG00000102572 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q9Y6E0 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| STU Query on STU | B [auth A] | STAUROSPORINE C28 H26 N4 O3 HKSZLNNOFSGOKW-FYTWVXJKSA-N |  | ||
| Modified Residues 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Type | Formula | 2D Diagram | Parent |
| TPO Query on TPO | A | L-PEPTIDE LINKING | C4 H10 N O6 P |  | THR |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.70 ?
- R-Value Free: 0.268
- R-Value Work: 0.204
- R-Value Observed: 0.204
- Space Group: P 1 21 1
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 47.369 | ¦Á = 90 |
| b = 54.766 | ¦Â = 114.69 |
| c = 61.136 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| PDB_EXTRACT | data extraction |
| MAR345 | data collection |
| DENZO | data reduction |
| SCALEPACK | data scaling |
| MOLREP | phasing |
Entry History
Deposition Data
- Released Date: 2008-04-29 Deposition Author(s): Antonysamy, S.S., Burley, S.K., Buchanan, S., Chau, F., Feil, I., Wu, L., Sauder, J.M., New York SGX Research Center for Structural Genomics (NYSGXRC)
Revision History (Full details and data files)
- Version 1.0: 2008-04-29
Type: Initial release - Version 1.1: 2011-07-13
Changes: Version format compliance - Version 1.2: 2017-10-25
Changes: Refinement description - Version 1.3: 2018-11-14
Changes: Data collection, Structure summary - Version 1.4: 2021-02-03
Changes: Database references, Derived calculations, Structure summary - Version 1.5: 2023-08-30
Changes: Data collection, Database references, Refinement description - Version 1.6: 2024-10-16
Changes: Structure summary
