3DXN

Crystal structure of the calcium-dependent kinase from toxoplasma gondii, 541.m00134, kinase domain.

PDB DOI: https://doi.org/10.2210/pdb3DXN/pdb

Classification: TRANSFERASE
Organism(s): Toxoplasma gondii
Expression System: Escherichia coli
Mutation(s): No

Deposited: 2008-07-24 Released: 2008-09-16
Deposition Author(s): Wernimont, A.K., Lew, J., Kozieradzki, I., Cossar, D., Wasney, G., Lin, Y.H., Hassani, A., Ali, A., Schapira, M., Bochkarev, A., Arrowsmith, C.H., Bountra, C., Wikstrom, M., Edwards, A.M., Hui, R., Artz, J.D., Amani, M., Structural Genomics Consortium (SGC)

Experimental Data Snapshot

Method: X-RAY DIFFRACTION
Resolution: 2.17 ?
R-Value Free: 0.265
R-Value Work: 0.230
R-Value Observed: 0.232

wwPDB Validation 3D Report Full Report

This is version 1.3 of the entry. See complete history.

Literature

Crystal structure of the calcium-dependent kinase from toxoplasma gondii, 541.m00134, kinase domain.

Wernimont, A.K., Lew, J., Kozieradzki, I., Cossar, D., Wasney, G., Lin, Y.H., Hassani, A., Ali, A., Schapira, M., Bochkarev, A., Arrowsmith, C.H., Bountra, C., Wikstrom, M., Edwards, A.M., Hui, R., Amani, M.

To be published.

Macromolecule Content

Total Structure Weight: 33.03 kDa
Atom Count: 2,110
Modelled Residue Count: 258
Deposited Residue Count: 287
Unique protein chains: 1

Macromolecules

Find similar proteins by:

(by identity cutoff) | 3D Structure

Entity ID: 1
Molecule	Chains	Sequence Length	Organism	Details	Image
Calmodulin-like domain protein kinase isoform 3	A	287	Toxoplasma gondii	Mutation(s): 0 Gene Names: 541.m00134
UniProt
Find proteins for Q3HNM6 (Toxoplasma gondii) Explore Q3HNM6 Go to UniProtKB: Q3HNM6
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	Q3HNM6
Sequence Annotations Expand
Reference Sequence

Experimental Data & Validation

Experimental Data

Method: X-RAY DIFFRACTION
Resolution: 2.17 ?
R-Value Free: 0.265
R-Value Work: 0.230
R-Value Observed: 0.232
Space Group: I 4

Unit Cell:

Length ( ? )	Angle ( ? )
a = 121.345	α = 90
b = 121.345	β = 90
c = 45.521	γ = 90

Software Package:

Software Name	Purpose
DENZO	data reduction
SCALEPACK	data scaling
PHASER	phasing
REFMAC	refinement
PDB_EXTRACT	data extraction

Structure Validation

View Full Validation Report

Entry History

Deposition Data

Released Date: 2008-09-16

Deposition Author(s):

Wernimont, A.K.

Kozieradzki, I.

Arrowsmith, C.H.

Structural Genomics Consortium (SGC)

Revision History (Full details and data files)

Version 1.0: 2008-09-16
Type: Initial release
Version 1.1: 2011-07-13
Changes: Advisory, Version format compliance
Version 1.2: 2017-10-25
Changes: Refinement description
Version 1.3: 2024-02-21
Changes: Data collection, Database references

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.