Download Mendeleyrystal structure of human cytosolic sulfotransferase SULT2A1 in complex with PAP and lithocholic acid
Pan, P.W., Dong, A., Amaya, M., Edwards, A.M.To be published.
3F3Y
Crystal structure of human cytosolic sulfotransferase SULT2A1 in complex with PAP and lithocholic acid
- PDB DOI: https://doi.org/10.2210/pdb3F3Y/pdb
- Classification: TRANSFERASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2008-10-31 Released: 2009-09-15
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.20 ?
- R-Value Free: 0.299
- R-Value Work: 0.236
- R-Value Observed: 0.238
This is version 1.2 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Bile salt sulfotransferase | 285 | Homo sapiens | Mutation(s): 0 Gene Names: HST, STD, SULT2A1 EC: 2.8.2.14 (PDB Primary Data), 2.8.2.2 (UniProt) |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q06520 (Homo sapiens) Explore Q06520 Go to UniProtKB: Q06520 | |||||
PHAROS: Q06520 GTEx: ENSG00000105398 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q06520 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| A3P Query on A3P | F [auth A], G [auth B], I [auth C], K [auth D] | ADENOSINE-3'-5'-DIPHOSPHATE C10 H15 N5 O10 P2 WHTCPDAXWFLDIH-KQYNXXCUSA-N |  | ||
| 4OA Query on 4OA | E [auth A], H [auth B], J [auth C], L [auth D] | (3beta,5beta,14beta,17alpha)-3-hydroxycholan-24-oic acid C24 H40 O3 SMEROWZSTRWXGI-HVATVPOCSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.20 ?
- R-Value Free: 0.299
- R-Value Work: 0.236
- R-Value Observed: 0.238
- Space Group: P 21 21 21
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 79.393 | ¦Á = 90 |
| b = 96.179 | ¦Â = 90 |
| c = 159.298 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| HKL-3000 | data collection |
| PHASER | phasing |
| REFMAC | refinement |
| Coot | model building |
| HKL-2000 | data reduction |
| HKL-2000 | data scaling |
Entry History
Deposition Data
- Released Date: 2009-09-15 Deposition Author(s): Pan, P.W., Dong, A., Amaya, M., Edwards, A.M.
Revision History (Full details and data files)
- Version 1.0: 2009-09-15
Type: Initial release - Version 1.1: 2011-07-13
Changes: Version format compliance - Version 1.2: 2023-12-27
Changes: Data collection, Database references, Derived calculations
