3J3Y | pdb_00003j3y

Atomic-level structure of the entire HIV-1 capsid (186 hexamers + 12 pentamers)


Experimental Data Snapshot

  • Method: ELECTRON MICROSCOPY
  • Aggregation State: PARTICLE 
  • Reconstruction Method: TOMOGRAPHY 

Starting Model: experimental
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This is version 1.5 of the entry. See complete history


Literature

Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics.

Zhao, G.Perilla, J.R.Yufenyuy, E.L.Meng, X.Chen, B.Ning, J.Ahn, J.Gronenborn, A.M.Schulten, K.Aiken, C.Zhang, P.

(2013) Nature 497: 643-646

  • DOI: https://doi.org/10.1038/nature12162
  • Primary Citation of Related Structures:  
    3J34, 3J3Q, 3J3Y, 3J4F

  • PubMed Abstract: 

    Retroviral capsid proteins are conserved structurally but assemble into different morphologies. The mature human immunodeficiency virus-1 (HIV-1) capsid is best described by a 'fullerene cone' model, in which hexamers of the capsid protein are linked to form a hexagonal surface lattice that is closed by incorporating 12 capsid-protein pentamers. HIV-1 capsid protein contains an amino-terminal domain (NTD) comprising seven ¦Á-helices and a ¦Â-hairpin, a carboxy-terminal domain (CTD) comprising four ¦Á-helices, and a flexible linker with a 310-helix connecting the two structural domains. Structures of the capsid-protein assembly units have been determined by X-ray crystallography; however, structural information regarding the assembled capsid and the contacts between the assembly units is incomplete. Here we report the cryo-electron microscopy structure of a tubular HIV-1 capsid-protein assembly at 8?? resolution and the three-dimensional structure of a native HIV-1 core by cryo-electron tomography. The structure of the tubular assembly shows, at the three-fold interface, a three-helix bundle with critical hydrophobic interactions. Mutagenesis studies confirm that hydrophobic residues in the centre of the three-helix bundle are crucial for capsid assembly and stability, and for viral infectivity. The cryo-electron-microscopy structures enable modelling by large-scale molecular dynamics simulation, resulting in all-atom models for the hexamer-of-hexamer and pentamer-of-hexamer elements as well as for the entire capsid. Incorporation of pentamers results in closer trimer contacts and induces acute surface curvature. The complete atomic HIV-1 capsid model provides a platform for further studies of capsid function and for targeted pharmacological intervention.


  • Organizational Affiliation

    Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15260, USA.


Macromolecules
Find similar proteins by:  (by identity cutoff)  |  3D Structure
Entity ID: 1
MoleculeChains Sequence LengthOrganismDetailsImage
capsid protein
A [auth g8],
AA [auth gw],
AAA [auth a4],
AB [auth gU],
ABA [auth as],
AC [auth hh],
ACA [auth aP],
AD [auth hF],
ADA [auth bd],
AE [auth i3],
AEA [auth bB],
AF [auth iq],
AFA [auth bY],
AG [auth iO],
AGA [auth cm],
AH [auth 28],
AHA [auth 1g],
AI [auth 2y],
AIA [auth d7],
AJ [auth 2Y],
AJA [auth dv],
AK [auth 3o],
AKA [auth dS],
AL [auth 3O],
ALA [auth eg],
AM [auth 4e],
AMA [auth eE],
AN [auth 4E],
ANA [auth f1],
AO [auth 54],
AOA [auth fp],
AP [auth 5u],
APA [auth fN],
AQ [auth 5U],
AQA [auth b],
AR [auth 6k],
ARA [auth z],
AS [auth 6K],
ASA [auth X],
AT [auth 7a],
AU [auth 7A],
AV [auth 80],
AW [auth 8q],
AX [auth 8Q],
AY [auth 9g],
AZ [auth 9G],
B [auth g9],
BA [auth gx],
BAA [auth a5],
BB [auth gV],
BBA [auth at],
BC [auth hi],
BCA [auth aQ],
BD [auth hG],
BDA [auth be],
BE [auth 1N],
BEA [auth 19],
BF [auth ir],
BFA [auth bZ],
BG [auth iP],
BGA [auth cn],
BH [auth 29],
BHA [auth cK],
BI [auth 2z],
BIA [auth d8],
BJ [auth 2Z],
BJA [auth dw],
BK [auth 3p],
BKA [auth dT],
BL [auth 3P],
BLA [auth eh],
BM [auth 4f],
BMA [auth eF],
BN [auth 4F],
BNA [auth f2],
BO [auth 55],
BOA [auth fq],
BP [auth 5v],
BPA [auth 1z],
BQ [auth 5V],
BQA [auth c],
BR [auth 6l],
BRA [auth A],
BS [auth 6L],
BSA [auth 5],
BT [auth 7b],
BU [auth 7B],
BV [auth 81],
BW [auth 8r],
BX [auth 8R],
BY [auth 9h],
BZ [auth 9H],
C [auth ga],
CA [auth gy],
CAA [auth a6],
CB [auth 1G],
CBA [auth 12],
CC [auth hj],
CCA [auth aR],
CD [auth hH],
CDA [auth bf],
CE [auth i4],
CEA [auth bC],
CF [auth is],
CFA [auth c0],
CG [auth iQ],
CGA [auth co],
CH [auth 2a],
CHA [auth cL],
CI [auth 2A],
CIA [auth d9],
CJ [auth 30],
CJA [auth dx],
CK [auth 3q],
CKA [auth dU],
CL [auth 3Q],
CLA [auth ei],
CM [auth 4g],
CMA [auth 1s],
CN [auth 4G],
CNA [auth f3],
CO [auth 56],
COA [auth fr],
CP [auth 5w],
CPA [auth fO],
CQ [auth 5W],
CQA [auth d],
CR [auth 6m],
CRA [auth B],
CS [auth 6M],
CSA [auth 6],
CT [auth 7c],
CU [auth 7C],
CV [auth 82],
CW [auth 8s],
CX [auth 8S],
CY [auth 9i],
CZ [auth 9I],
D [auth gb],
DA [auth gz],
DAA [auth a7],
DB [auth gW],
DBA [auth au],
DC [auth hk],
DCA [auth aS],
DD [auth hI],
DDA [auth bg],
DE [auth i5],
DEA [auth bD],
DF [auth it],
DFA [auth c1],
DG [auth iR],
DGA [auth cp],
DH [auth 2b],
DHA [auth cM],
DI [auth 2B],
DIA [auth da],
DJ [auth 31],
DJA [auth 1l],
DK [auth 3r],
DKA [auth dV],
DL [auth 3R],
DLA [auth ej],
DM [auth 4h],
DMA [auth eG],
DN [auth 4H],
DNA [auth f4],
DO [auth 57],
DOA [auth fs],
DP [auth 5x],
DPA [auth fP],
DQ [auth 5X],
DQA [auth e],
DR [auth 6n],
DRA [auth C],
DS [auth 6N],
DSA [auth 7],
DT [auth 7d],
DU [auth 7D],
DV [auth 83],
DW [auth 8t],
DX [auth 8T],
DY [auth 9j],
DZ [auth 9J],
E [auth gc],
EA [auth gA],
EAA [auth a8],
EB [auth gX],
EBA [auth av],
EC [auth hl],
ECA [auth aT],
ED [auth hJ],
EDA [auth bh],
EE [auth i6],
EEA [auth bE],
EF [auth iu],
EFA [auth c2],
EG [auth 1S],
EGA [auth 1e],
EH [auth 2c],
EHA [auth cN],
EI [auth 2C],
EIA [auth db],
EJ [auth 32],
EJA [auth dy],
EK [auth 3s],
EKA [auth dW],
EL [auth 3S],
ELA [auth ek],
EM [auth 4i],
EMA [auth eH],
EN [auth 4I],
ENA [auth f5],
EO [auth 58],
EOA [auth ft],
EP [auth 5y],
EPA [auth fQ],
EQ [auth 5Y],
EQA [auth f],
ER [auth 6o],
ERA [auth D],
ES [auth 6O],
ESA [auth 8],
ET [auth 7e],
EU [auth 7E],
EV [auth 84],
EW [auth 8u],
EX [auth 8U],
EY [auth 9k],
EZ [auth 9K],
F [auth gd],
FA [auth gB],
FAA [auth a9],
FB [auth gY],
FBA [auth aw],
FC [auth hm],
FCA [auth aU],
FD [auth 1L],
FDA [auth 17],
FE [auth i7],
FEA [auth bF],
FF [auth iv],
FFA [auth c3],
FG [auth iS],
FGA [auth cq],
FH [auth 2d],
FHA [auth cO],
FI [auth 2D],
FIA [auth dc],
FJ [auth 33],
FJA [auth dz],
FK [auth 3t],
FKA [auth dX],
FL [auth 3T],
FLA [auth el],
FM [auth 4j],
FMA [auth eI],
FN [auth 4J],
FNA [auth f6],
FO [auth 59],
FOA [auth 1x],
FP [auth 5z],
FPA [auth fR],
FQ [auth 5Z],
FQA [auth g],
FR [auth 6p],
FRA [auth 3],
FS [auth 6P],
FSA [auth 9],
FT [auth 7f],
FU [auth 7F],
FV [auth 85],
FW [auth 8v],
FX [auth 8V],
FY [auth 9l],
FZ [auth 9L],
G [auth ge],
GA [auth 1E],
GAA [auth 10],
GB [auth gZ],
GBA [auth ax],
GC [auth hn],
GCA [auth aV],
GD [auth hK],
GDA [auth bi],
GE [auth i8],
GEA [auth bG],
GF [auth iw],
GFA [auth c4],
GG [auth iT],
GGA [auth cr],
GH [auth 2e],
GHA [auth cP],
GI [auth 2E],
GIA [auth dd],
GJ [auth 34],
GJA [auth dA],
GK [auth 3u],
GKA [auth dY],
GL [auth 3U],
GLA [auth 1q],
GM [auth 4k],
GMA [auth eJ],
GN [auth 4K],
GNA [auth f7],
GO [auth 5a],
GOA [auth fu],
GP [auth 5A],
GPA [auth fS],
GQ [auth 60],
GQA [auth h],
GR [auth 6q],
GRA [auth E],
GS [auth 6Q],
GT [auth 7g],
GU [auth 7G],
GV [auth 86],
GW [auth 8w],
GX [auth 8W],
GY [auth 9m],
GZ [auth 9M],
H [auth gf],
HA [auth gC],
HAA [auth aa],
HB [auth h0],
HBA [auth ay],
HC [auth ho],
HCA [auth aW],
HD [auth hL],
HDA [auth bj],
HE [auth i9],
HEA [auth bH],
HF [auth ix],
HFA [auth c5],
HG [auth iU],
HGA [auth cs],
HH [auth 2f],
HHA [auth cQ],
HI [auth 2F],
HIA [auth 1j],
HJ [auth 35],
HJA [auth dB],
HK [auth 3v],
HKA [auth dZ],
HL [auth 3V],
HLA [auth em],
HM [auth 4l],
HMA [auth eK],
HN [auth 4L],
HNA [auth f8],
HO [auth 5b],
HOA [auth fv],
HP [auth 5B],
HPA [auth fT],
HQ [auth 61],
HQA [auth i],
HR [auth 6r],
HRA [auth F],
HS [auth 6R],
HT [auth 7h],
HU [auth 7H],
HV [auth 87],
HW [auth 8x],
HX [auth 8X],
HY [auth 9n],
HZ [auth 9N],
I [auth gg],
IA [auth gD],
IAA [auth ab],
IB [auth h1],
IBA [auth az],
IC [auth hp],
ICA [auth aX],
ID [auth hM],
IDA [auth bk],
IE [auth ia],
IEA [auth bI],
IF [auth 1Q],
IFA [auth 1c],
IG [auth iV],
IGA [auth ct],
IH [auth 2g],
IHA [auth cR],
II [auth 2G],
IIA [auth de],
IJ [auth 36],
IJA [auth dC],
IK [auth 3w],
IKA [auth e0],
IL [auth 3W],
ILA [auth en],
IM [auth 4m],
IMA [auth eL],
IN [auth 4M],
INA [auth f9],
IO [auth 5c],
IOA [auth fw],
IP [auth 5C],
IPA [auth fU],
IQ [auth 62],
IQA [auth j],
IR [auth 6s],
IRA [auth G],
IS [auth 6S],
IT [auth 7i],
IU [auth 7I],
IV [auth 88],
IW [auth 8y],
IX [auth 8Y],
IY [auth 9o],
IZ [auth 9O],
J [auth gh],
JA [auth gE],
JAA [auth ac],
JB [auth h2],
JBA [auth aA],
JC [auth 1J],
JCA [auth 15],
JD [auth hN],
JDA [auth bl],
JE [auth ib],
JEA [auth bJ],
JF [auth iy],
JFA [auth c6],
JG [auth iW],
JGA [auth cu],
JH [auth 2h],
JHA [auth cS],
JI [auth 2H],
JIA [auth df],
JJ [auth 37],
JJA [auth dD],
JK [auth 3x],
JKA [auth e1],
JL [auth 3X],
JLA [auth eo],
JM [auth 4n],
JMA [auth eM],
JN [auth 4N],
JNA [auth 1v],
JO [auth 5d],
JOA [auth fx],
JP [auth 5D],
JPA [auth fV],
JQ [auth 63],
JQA [auth 1],
JR [auth 6t],
JRA [auth H],
JS [auth 6T],
JT [auth 7j],
JU [auth 7J],
JV [auth 89],
JW [auth 8z],
JX [auth 8Z],
JY [auth 9p],
JZ [auth 9P],
K [auth 1C],
KA [auth gF],
KAA [auth ad],
KB [auth h3],
KBA [auth aB],
KC [auth hq],
KCA [auth aY],
KD [auth hO],
KDA [auth bm],
KE [auth ic],
KEA [auth bK],
KF [auth iz],
KFA [auth c7],
KG [auth iX],
KGA [auth cv],
KH [auth 2i],
KHA [auth cT],
KI [auth 2I],
KIA [auth dg],
KJ [auth 38],
KJA [auth dE],
KK [auth 3y],
KKA [auth 1o],
KL [auth 3Y],
KLA [auth ep],
KM [auth 4o],
KMA [auth eN],
KN [auth 4O],
KNA [auth fa],
KO [auth 5e],
KOA [auth fy],
KP [auth 5E],
KPA [auth fW],
KQ [auth 64],
KQA [auth k],
KR [auth 6u],
KRA [auth I],
KS [auth 6U],
KT [auth 7k],
KU [auth 7K],
KV [auth 8a],
KW [auth 8A],
KX [auth 90],
KY [auth 9q],
KZ [auth Y],
L [auth gi],
LA [auth gG],
LAA [auth ae],
LB [auth h4],
LBA [auth aC],
LC [auth hr],
LCA [auth aZ],
LD [auth hP],
LDA [auth bn],
LE [auth id],
LEA [auth bL],
LF [auth iA],
LFA [auth c8],
LG [auth 1T],
LGA [auth cw],
LH [auth 2j],
LHA [auth 1h],
LI [auth 2J],
LIA [auth dh],
LJ [auth 39],
LJA [auth dF],
LK [auth 3z],
LKA [auth e2],
LL [auth 3Z],
LLA [auth eq],
LM [auth 4p],
LMA [auth eO],
LN [auth 4P],
LNA [auth fb],
LO [auth 5f],
LOA [auth fz],
LP [auth 5F],
LPA [auth fX],
LQ [auth 65],
LQA [auth l],
LR [auth 6v],
LRA [auth J],
LS [auth 6V],
LT [auth 7l],
LU [auth 7L],
LV [auth 8b],
LW [auth 8B],
LX [auth 91],
LY [auth 9r],
LZ [auth 9Q],
M [auth gj],
MA [auth gH],
MAA [auth af],
MB [auth h5],
MBA [auth aD],
MC [auth hs],
MCA [auth b0],
MD [auth hQ],
MDA [auth bo],
ME [auth 1O],
MEA [auth 1a],
MF [auth iB],
MFA [auth c9],
MG [auth 1U],
MGA [auth cx],
MH [auth 2k],
MHA [auth cU],
MI [auth 2K],
MIA [auth di],
MJ [auth 3a],
MJA [auth dG],
MK [auth 3A],
MKA [auth e3],
ML [auth 40],
MLA [auth er],
MM [auth 4q],
MMA [auth eP],
MN [auth 4Q],
MNA [auth fc],
MO [auth 5g],
MOA [auth fA],
MP [auth 5G],
MPA [auth 1A],
MQ [auth 66],
MQA [auth m],
MR [auth 6w],
MRA [auth K],
MS [auth 6W],
MT [auth 7m],
MU [auth 7M],
MV [auth 8c],
MW [auth 8C],
MX [auth 92],
MY [auth 9s],
MZ [auth 9R],
N [auth gk],
NA [auth gI],
NAA [auth ag],
NB [auth 1H],
NBA [auth 13],
NC [auth ht],
NCA [auth b1],
ND [auth hR],
NDA [auth bp],
NE [auth ie],
NEA [auth bM],
NF [auth iC],
NFA [auth ca],
NG [auth 1V],
NGA [auth cy],
NH [auth 2l],
NHA [auth cV],
NI [auth 2L],
NIA [auth dj],
NJ [auth 3b],
NJA [auth dH],
NK [auth 3B],
NKA [auth e4],
NL [auth 41],
NLA [auth es],
NM [auth 4r],
NMA [auth 1t],
NN [auth 4R],
NNA [auth fd],
NO [auth 5h],
NOA [auth fB],
NP [auth 5H],
NPA [auth fY],
NQ [auth 67],
NQA [auth n],
NR [auth 6x],
NRA [auth L],
NS [auth 6X],
NT [auth 7n],
NU [auth 7N],
NV [auth 8d],
NW [auth 8D],
NX [auth 93],
NY [auth 9t],
NZ [auth 9S],
O [auth gl],
OA [auth gJ],
OAA [auth ah],
OB [auth h6],
OBA [auth aE],
OC [auth hu],
OCA [auth b2],
OD [auth hS],
ODA [auth bq],
OE [auth if],
OEA [auth bN],
OF [auth iD],
OFA [auth cb],
OG [auth 1W],
OGA [auth cz],
OH [auth 2m],
OHA [auth cW],
OI [auth 2M],
OIA [auth dk],
OJ [auth 3c],
OJA [auth 1m],
OK [auth 3C],
OKA [auth e5],
OL [auth 42],
OLA [auth et],
OM [auth 4s],
OMA [auth eQ],
ON [auth 4S],
ONA [auth fe],
OO [auth 5i],
OOA [auth fC],
OP [auth 5I],
OPA [auth fZ],
OQ [auth 68],
OQA [auth o],
OR [auth 6y],
ORA [auth M],
OS [auth 6Y],
OT [auth 7o],
OU [auth 7O],
OV [auth 8e],
OW [auth 8E],
OX [auth 94],
OY [auth 9u],
OZ [auth 9T],
P [auth gm],
PA [auth gK],
PAA [auth ai],
PB [auth h7],
PBA [auth aF],
PC [auth hv],
PCA [auth b3],
PD [auth hT],
PDA [auth br],
PE [auth ig],
PEA [auth bO],
PF [auth iE],
PFA [auth cc],
PG [auth 1X],
PGA [auth 1f],
PH [auth 2n],
PHA [auth cX],
PI [auth 2N],
PIA [auth dl],
PJ [auth 3d],
PJA [auth dI],
PK [auth 3D],
PKA [auth e6],
PL [auth 43],
PLA [auth eu],
PM [auth 4t],
PMA [auth eR],
PN [auth 4T],
PNA [auth ff],
PO [auth 5j],
POA [auth fD],
PP [auth 5J],
PPA [auth g0],
PQ [auth 69],
PQA [auth p],
PR [auth 6z],
PRA [auth N],
PS [auth 6Z],
PT [auth 7p],
PU [auth 7P],
PV [auth 8f],
PW [auth 8F],
PX [auth 95],
PY [auth 9v],
PZ [auth 9U],
Q [auth gn],
QA [auth gL],
QAA [auth aj],
QB [auth h8],
QBA [auth aG],
QC [auth hw],
QCA [auth b4],
QD [auth 1M],
QDA [auth 18],
QE [auth ih],
QEA [auth bP],
QF [auth iF],
QFA [auth cd],
QG [auth 1Y],
QGA [auth cA],
QH [auth 2o],
QHA [auth cY],
QI [auth 2O],
QIA [auth dm],
QJ [auth 3e],
QJA [auth dJ],
QK [auth 3E],
QKA [auth e7],
QL [auth 44],
QLA [auth ev],
QM [auth 4u],
QMA [auth eS],
QN [auth 4U],
QNA [auth fg],
QO [auth 5k],
QOA [auth 1y],
QP [auth 5K],
QPA [auth g1],
QQ [auth 6a],
QQA [auth q],
QR [auth 6A],
QRA [auth 4],
QS [auth 70],
QT [auth 7q],
QU [auth 7Q],
QV [auth 8g],
QW [auth 8G],
QX [auth 96],
QY [auth 9w],
QZ [auth 9V],
R [auth go],
RA [auth 1F],
RAA [auth 11],
RB [auth h9],
RBA [auth aH],
RC [auth hx],
RCA [auth b5],
RD [auth hU],
RDA [auth bs],
RE [auth ii],
REA [auth bQ],
RF [auth iG],
RFA [auth ce],
RG [auth 1Z],
RGA [auth cB],
RH [auth 2p],
RHA [auth cZ],
RI [auth 2P],
RIA [auth dn],
RJ [auth 3f],
RJA [auth dK],
RK [auth 3F],
RKA [auth e8],
RL [auth 45],
RLA [auth 1r],
RM [auth 4v],
RMA [auth eT],
RN [auth 4V],
RNA [auth fh],
RO [auth 5l],
ROA [auth fE],
RP [auth 5L],
RPA [auth g2],
RQ [auth 6b],
RQA [auth r],
RR [auth 6B],
RRA [auth O],
RS [auth 71],
RT [auth 7r],
RU [auth 7R],
RV [auth 8h],
RW [auth 8H],
RX [auth 97],
RY [auth 9x],
RZ [auth 9W],
S [auth gp],
SA [auth gM],
SAA [auth ak],
SB [auth ha],
SBA [auth aI],
SC [auth hy],
SCA [auth b6],
SD [auth hV],
SDA [auth bt],
SE [auth ij],
SEA [auth bR],
SF [auth iH],
SFA [auth cf],
SG [auth 20],
SGA [auth cC],
SH [auth 2q],
SHA [auth d0],
SI [auth 2Q],
SIA [auth 1k],
SJ [auth 3g],
SJA [auth dL],
SK [auth 3G],
SKA [auth e9],
SL [auth 46],
SLA [auth ew],
SM [auth 4w],
SMA [auth eU],
SN [auth 4W],
SNA [auth fi],
SO [auth 5m],
SOA [auth fF],
SP [auth 5M],
SPA [auth g3],
SQ [auth 6c],
SQA [auth s],
SR [auth 6C],
SRA [auth P],
SS [auth 72],
ST [auth 7s],
SU [auth 7S],
SV [auth 8i],
SW [auth 8I],
SX [auth 98],
SY [auth 9y],
SZ [auth 9X],
T [auth gq],
TA [auth gN],
TAA [auth al],
TB [auth hb],
TBA [auth aJ],
TC [auth hz],
TCA [auth b7],
TD [auth hW],
TDA [auth bu],
TE [auth ik],
TEA [auth bS],
TF [auth 1R],
TFA [auth 1d],
TG [auth 21],
TGA [auth cD],
TH [auth 2r],
THA [auth d1],
TI [auth 2R],
TIA [auth do],
TJ [auth 3h],
TJA [auth dM],
TK [auth 3H],
TKA [auth ea],
TL [auth 47],
TLA [auth ex],
TM [auth 4x],
TMA [auth eV],
TN [auth 4X],
TNA [auth fj],
TO [auth 5n],
TOA [auth fG],
TP [auth 5N],
TPA [auth g4],
TQ [auth 6d],
TQA [auth t],
TR [auth 6D],
TRA [auth Q],
TS [auth 73],
TT [auth 7t],
TU [auth 7T],
TV [auth 8j],
TW [auth 8J],
TX [auth 99],
TY [auth 9z],
TZ [auth 9Y],
U [auth gr],
UA [auth gO],
UAA [auth am],
UB [auth hc],
UBA [auth aK],
UC [auth 1K],
UCA [auth 16],
UD [auth hX],
UDA [auth bv],
UE [auth il],
UEA [auth bT],
UF [auth iI],
UFA [auth cg],
UG [auth 22],
UGA [auth cE],
UH [auth 2s],
UHA [auth d2],
UI [auth 2S],
UIA [auth dp],
UJ [auth 3i],
UJA [auth dN],
UK [auth 3I],
UKA [auth eb],
UL [auth 48],
ULA [auth ey],
UM [auth 4y],
UMA [auth eW],
UN [auth 4Y],
UNA [auth 1w],
UO [auth 5o],
UOA [auth fH],
UP [auth 5O],
UPA [auth g5],
UQ [auth 6e],
UQA [auth 2],
UR [auth 6E],
URA [auth R],
US [auth 74],
UT [auth 7u],
UU [auth 7U],
UV [auth 8k],
UW [auth 8K],
UX [auth 9a],
UY [auth 9A],
UZ [auth 9Z],
V [auth 1D],
VA [auth gP],
VAA [auth an],
VB [auth hd],
VBA [auth aL],
VC [auth hA],
VCA [auth b8],
VD [auth hY],
VDA [auth bw],
VE [auth im],
VEA [auth bU],
VF [auth iJ],
VFA [auth ch],
VG [auth 23],
VGA [auth cF],
VH [auth 2t],
VHA [auth d3],
VI [auth 2T],
VIA [auth dq],
VJ [auth 3j],
VJA [auth dO],
VK [auth 3J],
VKA [auth 1p],
VL [auth 49],
VLA [auth ez],
VM [auth 4z],
VMA [auth eX],
VN [auth 4Z],
VNA [auth fk],
VO [auth 5p],
VOA [auth fI],
VP [auth 5P],
VPA [auth g6],
VQ [auth 6f],
VQA [auth u],
VR [auth 6F],
VRA [auth S],
VS [auth 75],
VT [auth 7v],
VU [auth 7V],
VV [auth 8l],
VW [auth 8L],
VX [auth 9b],
VY [auth 9B],
VZ [auth Z],
W [auth gs],
WA [auth gQ],
WAA [auth ao],
WB [auth he],
WBA [auth aM],
WC [auth hB],
WCA [auth b9],
WD [auth hZ],
WDA [auth bx],
WE [auth in],
WEA [auth bV],
WF [auth iK],
WFA [auth ci],
WG [auth 24],
WGA [auth cG],
WH [auth 2u],
WHA [auth 1i],
WI [auth 2U],
WIA [auth dr],
WJ [auth 3k],
WJA [auth dP],
WK [auth 3K],
WKA [auth ec],
WL [auth 4a],
WLA [auth eA],
WM [auth 4A],
WMA [auth eY],
WN [auth 50],
WNA [auth fl],
WO [auth 5q],
WOA [auth fJ],
WP [auth 5Q],
WPA [auth g7],
WQ [auth 6g],
WQA [auth v],
WR [auth 6G],
WRA [auth T],
WS [auth 76],
WT [auth 7w],
WU [auth 7W],
WV [auth 8m],
WW [auth 8M],
WX [auth 9c],
WY [auth 9C],
WZ [auth a0],
X [auth gt],
XA [auth gR],
XAA [auth ap],
XB [auth hf],
XBA [auth aN],
XC [auth hC],
XCA [auth ba],
XD [auth i0],
XDA [auth by],
XE [auth 1P],
XEA [auth 1b],
XF [auth iL],
XFA [auth cj],
XG [auth 25],
XGA [auth cH],
XH [auth 2v],
XHA [auth d4],
XI [auth 2V],
XIA [auth ds],
XJ [auth 3l],
XJA [auth dQ],
XK [auth 3L],
XKA [auth ed],
XL [auth 4b],
XLA [auth eB],
XM [auth 4B],
XMA [auth eZ],
XN [auth 51],
XNA [auth fm],
XO [auth 5r],
XOA [auth fK],
XP [auth 5R],
XPA [auth 1B],
XQ [auth 6h],
XQA [auth w],
XR [auth 6H],
XRA [auth U],
XS [auth 77],
XT [auth 7x],
XU [auth 7X],
XV [auth 8n],
XW [auth 8N],
XX [auth 9d],
XY [auth 9D],
XZ [auth a1],
Y [auth gu],
YA [auth gS],
YAA [auth aq],
YB [auth 1I],
YBA [auth 14],
YC [auth hD],
YCA [auth bb],
YD [auth i1],
YDA [auth bz],
YE [auth io],
YEA [auth bW],
YF [auth iM],
YFA [auth ck],
YG [auth 26],
YGA [auth cI],
YH [auth 2w],
YHA [auth d5],
YI [auth 2W],
YIA [auth dt],
YJ [auth 3m],
YJA [auth dR],
YK [auth 3M],
YKA [auth ee],
YL [auth 4c],
YLA [auth eC],
YM [auth 4C],
YMA [auth 1u],
YN [auth 52],
YNA [auth fn],
YO [auth 5s],
YOA [auth fL],
YP [auth 5S],
YPA [auth 0],
YQ [auth 6i],
YQA [auth x],
YR [auth 6I],
YRA [auth V],
YS [auth 78],
YT [auth 7y],
YU [auth 7Y],
YV [auth 8o],
YW [auth 8O],
YX [auth 9e],
YY [auth 9E],
YZ [auth a2],
Z [auth gv],
ZA [auth gT],
ZAA [auth ar],
ZB [auth hg],
ZBA [auth aO],
ZC [auth hE],
ZCA [auth bc],
ZD [auth i2],
ZDA [auth bA],
ZE [auth ip],
ZEA [auth bX],
ZF [auth iN],
ZFA [auth cl],
ZG [auth 27],
ZGA [auth cJ],
ZH [auth 2x],
ZHA [auth d6],
ZI [auth 2X],
ZIA [auth du],
ZJ [auth 3n],
ZJA [auth 1n],
ZK [auth 3N],
ZKA [auth ef],
ZL [auth 4d],
ZLA [auth eD],
ZM [auth 4D],
ZMA [auth f0],
ZN [auth 53],
ZNA [auth fo],
ZO [auth 5t],
ZOA [auth fM],
ZP [auth 5T],
ZPA [auth a],
ZQ [auth 6j],
ZQA [auth y],
ZR [auth 6J],
ZRA [auth W],
ZS [auth 79],
ZT [auth 7z],
ZU [auth 7Z],
ZV [auth 8p],
ZW [auth 8P],
ZX [auth 9f],
ZY [auth 9F],
ZZ [auth a3]
231Human immunodeficiency virus 1Mutation(s): 1 
Gene Names: gag
UniProt
Find proteins for Q79791 (Human immunodeficiency virus type 1 group M subtype B (isolate NY5))
Explore Q79791 
Go to UniProtKB:  Q79791
Entity Groups  
Sequence Clusters30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt GroupQ79791
Sequence Annotations
Expand
  • Reference Sequence
Experimental Data & Validation

Experimental Data

  • Method: ELECTRON MICROSCOPY
  • Aggregation State: PARTICLE 
  • Reconstruction Method: TOMOGRAPHY 
EM Software:
TaskSoftware PackageVersion
RECONSTRUCTIONTOMO3D

Structure Validation

View Full Validation Report

Currently 3J3Y does not have a validation slider image.



Entry History 

Deposition Data

Revision History  (Full details and data files)

  • Version 1.0: 2013-05-29
    Type: Initial release
  • Version 1.1: 2013-06-12
    Changes: Database references
  • Version 1.2: 2014-07-09
    Changes: Other
  • Version 1.3: 2014-12-10
    Changes: Other
  • Version 1.4: 2018-07-18
    Changes: Data collection
  • Version 1.5: 2024-11-06
    Changes: Data collection, Database references, Refinement description, Structure summary
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