Download MendeleyStructural and functional analysis of the flexible regions of the catalytic alpha-subunit of protein kinase CK2
Papinutto, E., Ranchio, A., Lolli, G., Pinna, L.A., Battistutta, R.To be published.
3PZH
Crystal structure of maize CK2 alpha in complex with emodin at 1.92 A resolution
- PDB DOI: https://doi.org/10.2210/pdb3PZH/pdb
- Classification: TRANSFERASE/TRANSFERASE INHIBITOR
- Organism(s): Zea mays
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2010-12-14 Released: 2011-12-21
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.92 ?
- R-Value Free: 0.209
- R-Value Work: 0.159
- R-Value Observed: 0.161
This is version 1.2 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Casein kinase II subunit alpha | 332 | Zea mays | Mutation(s): 0 Gene Names: ACK2 EC: 2.7.11.1 |  | |
UniProt | |||||
Find proteins for P28523 (Zea mays) Explore P28523 Go to UniProtKB: P28523 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P28523 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 4 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| EMO Query on EMO | B [auth A] | 3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE C15 H10 O5 RHMXXJGYXNZAPX-UHFFFAOYSA-N |  | ||
| EDO Query on EDO | E [auth A] F [auth A] G [auth A] H [auth A] I [auth A] | 1,2-ETHANEDIOL C2 H6 O2 LYCAIKOWRPUZTN-UHFFFAOYSA-N |  | ||
| ACT Query on ACT | C [auth A], D [auth A] | ACETATE ION C2 H3 O2 QTBSBXVTEAMEQO-UHFFFAOYSA-M |  | ||
| CL Query on CL | M [auth A] | CHLORIDE ION Cl VEXZGXHMUGYJMC-UHFFFAOYSA-M |  | ||
| Modified Residues 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Type | Formula | 2D Diagram | Parent |
| CME Query on CME | A | L-PEPTIDE LINKING | C5 H11 N O3 S2 |  | CYS |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.92 ?
- R-Value Free: 0.209
- R-Value Work: 0.159
- R-Value Observed: 0.161
- Space Group: C 1 2 1
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 142.629 | ¦Á = 90 |
| b = 59.376 | ¦Â = 103.06 |
| c = 44.86 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| SCALA | data scaling |
| PHENIX | refinement |
| PDB_EXTRACT | data extraction |
| ProDC | data collection |
| XSCALE | data scaling |
Entry History
Deposition Data
- Released Date: 2011-12-21 Deposition Author(s): Battistutta, R., Mazzorana, M.
Revision History (Full details and data files)
- Version 1.0: 2011-12-21
Type: Initial release - Version 1.1: 2017-11-08
Changes: Refinement description - Version 1.2: 2024-11-06
Changes: Data collection, Database references, Derived calculations, Structure summary
