Download MendeleyCrystal structures of falcilysin, a M16 metalloprotease from the malaria parasite Plasmodium falciparum
Morgunova, E., Ponpuak, M., Istvan, E., Popov, A., Goldberg, D., Eneqvist, T.To be published.
3S5M
Crystal structures of falcilysin, a M16 metalloprotease from the malaria parasite Plasmodium falciparum
- PDB DOI: https://doi.org/10.2210/pdb3S5M/pdb
- Classification: HYDROLASE
- Organism(s): Plasmodium falciparum HB3
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2011-05-23 Released: 2012-05-23
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.55 ?
- R-Value Free: 0.214
- R-Value Work: 0.179
- R-Value Observed: 0.180
Starting Model: experimental
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wwPDB Validation 3D Report Full Report
This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
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(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Falcilysin | 1,193 | Plasmodium falciparum HB3 | Mutation(s): 0 Gene Names: flN, PF13_0322 EC: 3.4.24 |  | |
UniProt | |||||
Find proteins for Q76NL8 (Plasmodium falciparum (isolate 3D7)) Explore Q76NL8 Go to UniProtKB: Q76NL8 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q76NL8 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| ZN Query on ZN | B [auth A] | ZINC ION Zn PTFCDOFLOPIGGS-UHFFFAOYSA-N |  | ||
| MG Query on MG | C [auth A], D [auth A] | MAGNESIUM ION Mg JLVVSXFLKOJNIY-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.55 ?
- R-Value Free: 0.214
- R-Value Work: 0.179
- R-Value Observed: 0.180
- Space Group: P 21 21 21
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 94.32 | ¦Á = 90 |
| b = 106.7 | ¦Â = 90 |
| c = 128.02 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| ADSC | data collection |
| PHENIX | model building |
| PHENIX | refinement |
| XDS | data reduction |
| SCALA | data scaling |
| PHENIX | phasing |
Entry History
Deposition Data
- Released Date: 2012-05-23 Deposition Author(s): Morgunova, E., Ponpuak, M., Istvan, E., Popov, A., Goldberg, D., Eneqvist, T.
Revision History (Full details and data files)
- Version 1.0: 2012-05-23
Type: Initial release - Version 1.1: 2023-09-13
Changes: Data collection, Database references, Derived calculations, Refinement description
