Download MendeleyAn Enzyme at Atomic Resolution: The 1.05 A Structure of Salmonella Typhimurium Neuraminidase (Sialidase)
Garman, E.F., Wouters, J., Schneider, T.R., Vimr, E.R., Laver, W.G., Sheldrick, G.M.To be published.
3SIL
SIALIDASE FROM SALMONELLA TYPHIMURIUM
- PDB DOI: https://doi.org/10.2210/pdb3SIL/pdb
- Classification: GLYCOSIDASE
- Organism(s): Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
- Expression System: Escherichia coli
- Mutation(s): Yes
- Deposited: 1998-07-07 Released: 1998-11-11
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.05 ?
- R-Value Free: 0.147
- R-Value Observed: 0.116
Starting Model: experimental
View more details
wwPDB Validation 3D Report Full Report
This is version 1.5 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| SIALIDASE | 379 | Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 | Mutation(s): 1 Gene Names: NANH EC: 3.2.1.18 |  | |
UniProt | |||||
Find proteins for P29768 (Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)) Explore P29768 Go to UniProtKB: P29768 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P29768 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 3 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| PO4 Query on PO4 | C [auth A] | PHOSPHATE ION O4 P NBIIXXVUZAFLBC-UHFFFAOYSA-K |  | ||
| GOL Query on GOL | D [auth A] E [auth A] F [auth A] G [auth A] H [auth A] | GLYCEROL C3 H8 O3 PEDCQBHIVMGVHV-UHFFFAOYSA-N |  | ||
| K Query on K | B [auth A] | POTASSIUM ION K NPYPAHLBTDXSSS-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.05 ?
- R-Value Free: 0.147
- R-Value Observed: 0.116
- Space Group: P 21 21 21
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 47.1 | ¦Á = 90 |
| b = 81.73 | ¦Â = 90 |
| c = 91.5 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| DENZO | data reduction |
| SCALEPACK | data scaling |
| SHELXL-97 | refinement |
Entry History
Deposition Data
- Released Date: 1998-11-11 Deposition Author(s): Garman, E.F., Sheldrick, G.M.
Revision History (Full details and data files)
- Version 1.0: 1998-11-11
Type: Initial release - Version 1.1: 2008-03-25
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Source and taxonomy, Version format compliance - Version 1.3: 2021-11-03
Changes: Data collection, Database references, Derived calculations - Version 1.4: 2023-08-09
Changes: Refinement description - Version 1.5: 2024-10-09
Changes: Data collection, Structure summary
