Download MendeleyStructure of Mycobacterium tuberculosis GlmU in complex with Acetyl CoA
Jagtap, P.A., Prakash, B.To be published.
3ST8
Crystal structure of GlmU from Mycobacterium tuberculosis in complex with COENZYME A, GLUCOSAMINE 1-PHOSPHATE and URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE
- PDB DOI: https://doi.org/10.2210/pdb3ST8/pdb
- Classification: TRANSFERASE
- Organism(s): Mycobacterium tuberculosis H37Rv
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2011-07-09 Released: 2012-08-08
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.98 ?
- R-Value Free: 0.202
- R-Value Work: 0.167
- R-Value Observed: 0.168
This is version 2.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Bifunctional protein glmU | 501 | Mycobacterium tuberculosis H37Rv | Mutation(s): 0 Gene Names: glmU, MT1046, Rv1018c EC: 2.7.7.23 (PDB Primary Data), 2.3.1.157 (PDB Primary Data) |  | |
UniProt | |||||
Find proteins for P9WMN3 (Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)) Explore P9WMN3 Go to UniProtKB: P9WMN3 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P9WMN3 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 4 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| COA Query on COA | D [auth A] | COENZYME A C21 H36 N7 O16 P3 S RGJOEKWQDUBAIZ-IBOSZNHHSA-N |  | ||
| UD1 Query on UD1 | H [auth A] | URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE C17 H27 N3 O17 P2 LFTYTUAZOPRMMI-CFRASDGPSA-N |  | ||
| GP1 Query on GP1 | E [auth A] | 2-amino-2-deoxy-1-O-phosphono-alpha-D-glucopyranose C6 H14 N O8 P YMJBYRVFGYXULK-QZABAPFNSA-N |  | ||
| MG Query on MG | B [auth A], C [auth A], F [auth A], G [auth A] | MAGNESIUM ION Mg JLVVSXFLKOJNIY-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.98 ?
- R-Value Free: 0.202
- R-Value Work: 0.167
- R-Value Observed: 0.168
- Space Group: H 3 2
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 110.312 | ¦Á = 90 |
| b = 110.312 | ¦Â = 90 |
| c = 360.537 | ¦Ă = 120 |
| Software Name | Purpose |
|---|---|
| XSCALE | data scaling |
| REFMAC | refinement |
| PDB_EXTRACT | data extraction |
Entry History
Deposition Data
- Released Date: 2012-08-08 Deposition Author(s): Jagtap, P.A., Prakash, B.
Revision History (Full details and data files)
- Version 1.0: 2012-08-08
Type: Initial release - Version 2.0: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Atomic model, Data collection, Database references, Derived calculations, Structure summary - Version 2.1: 2024-03-20
Changes: Data collection, Database references, Structure summary
