Download MendeleyIdentification of the Activating Anion Binding Site in Human Phosphoglycerate Kinase
Bowler, M.W.To be published.
3ZOZ
The structure of human phosphoglycerate kinase with bound bromide, a stimulating anion.
- PDB DOI: https://doi.org/10.2210/pdb3ZOZ/pdb
- Classification: TRANSFERASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli BL21
- Mutation(s): No
- Deposited: 2013-02-26 Released: 2014-03-12
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.95 ?
- R-Value Free: 0.209
- R-Value Work: 0.161
- R-Value Observed: 0.164
Starting Model: experimental
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This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| PHOSPHOGLYCERATE KINASE 1 | 417 | Homo sapiens | Mutation(s): 0 EC: 2.7.2.3 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P00558 (Homo sapiens) Explore P00558 Go to UniProtKB: P00558 | |||||
PHAROS: P00558 GTEx: ENSG00000102144 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P00558 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 5 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| ADP Query on ADP | F [auth A] | ADENOSINE-5'-DIPHOSPHATE C10 H15 N5 O10 P2 XTWYTFMLZFPYCI-KQYNXXCUSA-N |  | ||
| 3PG Query on 3PG | E [auth A] | 3-PHOSPHOGLYCERIC ACID C3 H7 O7 P OSJPPGNTCRNQQC-UWTATZPHSA-N |  | ||
| MGF Query on MGF | D [auth A] | TRIFLUOROMAGNESATE F3 Mg GJOMWUHGUQLOAC-UHFFFAOYSA-K |  | ||
| BR Query on BR | C [auth A] | BROMIDE ION Br CPELXLSAUQHCOX-UHFFFAOYSA-M |  | ||
| MG Query on MG | B [auth A] | MAGNESIUM ION Mg JLVVSXFLKOJNIY-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.95 ?
- R-Value Free: 0.209
- R-Value Work: 0.161
- R-Value Observed: 0.164
- Space Group: P 21 21 21
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 38.98 | ¦Á = 90 |
| b = 91.81 | ¦Â = 90 |
| c = 108.21 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| MOSFLM | data reduction |
| SCALA | data scaling |
| MOLREP | phasing |
Entry History
Deposition Data
- Released Date: 2014-03-12 Deposition Author(s): Bowler, M.W.
Revision History (Full details and data files)
- Version 1.0: 2014-03-12
Type: Initial release - Version 1.1: 2023-12-20
Changes: Data collection, Database references, Derived calculations, Other, Refinement description
