Download MendeleyLeismania major dihydroorotate in complex with orotate
Cordeiro, A.T., Feliciano, P.R., Nonato, M.C.To be published.
3GZ3
Leishmania major Dihydroorotate Dehydrogenase in complex with orotate
- PDB DOI: https://doi.org/10.2210/pdb3GZ3/pdb
- Classification: OXIDOREDUCTASE
- Organism(s): Leishmania major
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2009-04-06 Released: 2010-04-28
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.90 ?
- R-Value Free: 0.204
- R-Value Work: 0.177
- R-Value Observed: 0.178
Starting Model: experimental
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This is version 1.2 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Dihydroorotate dehydrogenase, putative | 354 | Leishmania major | Mutation(s): 0 Gene Names: LmjF16.0530, pyrD EC: 1.3.3.1 (PDB Primary Data), 1.3.98.1 (UniProt) |  | |
UniProt | |||||
Find proteins for Q4QEW7 (Leishmania major) Explore Q4QEW7 Go to UniProtKB: Q4QEW7 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q4QEW7 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 3 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| FMN Query on FMN | C [auth A], G [auth B] | FLAVIN MONONUCLEOTIDE C17 H21 N4 O9 P FVTCRASFADXXNN-SCRDCRAPSA-N |  | ||
| ORO Query on ORO | D [auth A], H [auth B] | OROTIC ACID C5 H4 N2 O4 PXQPEWDEAKTCGB-UHFFFAOYSA-N |  | ||
| GOL Query on GOL | E [auth A], F [auth A], I [auth B], J [auth B] | GLYCEROL C3 H8 O3 PEDCQBHIVMGVHV-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.90 ?
- R-Value Free: 0.204
- R-Value Work: 0.177
- R-Value Observed: 0.178
- Space Group: P 61
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 142.167 | ¦Á = 90 |
| b = 142.167 | ¦Â = 90 |
| c = 69.157 | ¦Ă = 120 |
| Software Name | Purpose |
|---|---|
| HKL-2000 | data collection |
| MOLREP | phasing |
| REFMAC | refinement |
| MOSFLM | data reduction |
| SCALA | data scaling |
Entry History
Deposition Data
- Released Date: 2010-04-28 Deposition Author(s): Cordeiro, A.T., Feliciano, P.R., Nonato, M.C.
Revision History (Full details and data files)
- Version 1.0: 2010-04-28
Type: Initial release - Version 1.1: 2011-07-13
Changes: Version format compliance - Version 1.2: 2023-09-06
Changes: Data collection, Database references, Derived calculations, Refinement description
