Download MendeleyInosine 5'-monophosphate dehydrogenase from Vibrio cholerae, deletion mutant, in complex with NAD and IMP
Osipiuk, J., Maltseva, N., Makowska-Grzyska, M., Gu, M., Anderson, W.F., Joachimiak, A.To be published.
4QNE
Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae, deletion mutant, in complex with NAD and IMP
- PDB DOI: https://doi.org/10.2210/pdb4QNE/pdb
- Entry: 4QNE supersedes: 4HLV
- Classification: OXIDOREDUCTASE
- Organism(s): Vibrio cholerae O1 biovar El Tor str. N16961
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2014-06-17 Released: 2014-08-06
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.32 ?
- R-Value Free: 0.270
- R-Value Work: 0.196
- R-Value Observed: 0.200
Starting Model: experimental
View more details
This is version 1.3 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Inosine 5'-monophosphate dehydrogenase | 366 | Vibrio cholerae O1 biovar El Tor str. N16961 | Mutation(s): 0 Gene Names: VC0767 EC: 1.1.1.205 |  | |
UniProt | |||||
Find proteins for Q9KTW3 (Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)) Explore Q9KTW3 Go to UniProtKB: Q9KTW3 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q9KTW3 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 3 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| NAJ Query on NAJ | D [auth A], G [auth B] | NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM) C21 H27 N7 O14 P2 BAWFJGJZGIEFAR-NNYOXOHSSA-N |  | ||
| IMP Query on IMP | C [auth A], F [auth B] | INOSINIC ACID C10 H13 N4 O8 P GRSZFWQUAKGDAV-KQYNXXCUSA-N |  | ||
| K Query on K | E [auth A], H [auth B] | POTASSIUM ION K NPYPAHLBTDXSSS-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.32 ?
- R-Value Free: 0.270
- R-Value Work: 0.196
- R-Value Observed: 0.200
- Space Group: P 4 21 2
- Diffraction Data: https://doi.org/10.18430/m34qne
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 121.334 | ¦Á = 90 |
| b = 121.334 | ¦Â = 90 |
| c = 94.47 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| DENZO | data reduction |
| SCALEPACK | data scaling |
| REFMAC | refinement |
| PDB_EXTRACT | data extraction |
| SBC-Collect | data collection |
| HKL-3000 | data reduction |
| HKL-3000 | data scaling |
| MOLREP | phasing |
| HKL-3000 | phasing |
Entry History
Deposition Data
- Released Date: 2014-08-06 Deposition Author(s): Osipiuk, J., Maltseva, N., Makowska-Grzyska, M., Gu, M., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
- This entry supersedes: 4HLV
Revision History (Full details and data files)
- Version 1.0: 2014-08-06
Type: Initial release - Version 1.1: 2017-07-26
Changes: Source and taxonomy - Version 1.2: 2017-11-22
Changes: Refinement description - Version 1.3: 2023-09-20
Changes: Data collection, Database references, Derived calculations, Refinement description
