Download MendeleyCrystal structure of unliganded human FPPS at 2.15 angstrom resolution
Park, J., Berghuis, A.M.To be published.
4XQR
Crystal structure of unliganded human FPPS at 2.15 angstrom resolution
- PDB DOI: https://doi.org/10.2210/pdb4XQR/pdb
- Classification: TRANSFERASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2015-01-20 Released: 2016-01-20
- Funding Organization(s): Fonds de recherche Nature et technologies
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.15 ?
- R-Value Free: 0.225
- R-Value Work: 0.185
- R-Value Observed: 0.187
Starting Model: experimental
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wwPDB Validation 3D Report Full Report
This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Farnesyl pyrophosphate synthase | A [auth F] | 375 | Homo sapiens | Mutation(s): 0 Gene Names: FDPS, FPS, KIAA1293 EC: 2.5.1.10 (PDB Primary Data), 2.5.1.1 (PDB Primary Data) |  |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P14324 (Homo sapiens) Explore P14324 Go to UniProtKB: P14324 | |||||
PHAROS: P14324 GTEx: ENSG00000160752 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P14324 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| PO4 Query on PO4 | B [auth F] | PHOSPHATE ION O4 P NBIIXXVUZAFLBC-UHFFFAOYSA-K |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.15 ?
- R-Value Free: 0.225
- R-Value Work: 0.185
- R-Value Observed: 0.187
- Space Group: P 41 21 2
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 110.85 | ¦Á = 90 |
| b = 110.85 | ¦Â = 90 |
| c = 78.08 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| XDS | data reduction |
| XSCALE | data scaling |
| REFMAC | phasing |
Entry History & Funding Information
Deposition Data
- Released Date: 2016-01-20 Deposition Author(s): Park, J., Berghuis, A.M.
| Funding Organization | Location | Grant Number |
|---|---|---|
| Fonds de recherche Nature et technologies | Canada | -- |
Revision History (Full details and data files)
- Version 1.0: 2016-01-20
Type: Initial release - Version 1.1: 2023-09-27
Changes: Data collection, Database references, Derived calculations, Refinement description
