Download MendeleyGABA-aminotransferase inactivated by conformationally-restricted inactivator
Lee, H.V., Dustin, D.H., Wu, R., Emma, D., Sanishvili, R., Liu, D., Neil, K., Silverman, R.B.To be published.
4Y0I
GABA-aminotransferase inactivated by conformationally-restricted inactivator
- PDB DOI: https://doi.org/10.2210/pdb4Y0I/pdb
- Classification: TRANSFERASE
- Organism(s): Sus scrofa
- Expression System: Sus barbatus
- Mutation(s): No
- Deposited: 2015-02-06 Released: 2016-02-17
- Funding Organization(s): National Institutes of Health/National Cancer Institute (NIH/NCI)
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.66 ?
- R-Value Free: 0.204
- R-Value Work: 0.172
- R-Value Observed: 0.173
This is version 1.3 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| 4-aminobutyrate aminotransferase, mitochondrial | 461 | Sus scrofa | Mutation(s): 0 Gene Names: ABAT, GABAT EC: 2.6.1.19 (PDB Primary Data), 2.6.1.22 (PDB Primary Data) |  | |
UniProt | |||||
Find proteins for P80147 (Sus scrofa) Explore P80147 Go to UniProtKB: P80147 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P80147 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 3 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| PSZ Query on PSZ | E [auth A], H [auth B], K [auth C], L [auth D] | 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]THIOPHENE-2-CARBOXYLIC ACID C13 H15 N2 O7 P S SUKBSASAEROGCJ-UHFFFAOYSA-N |  | ||
| FES Query on FES | F [auth A], J [auth C] | FE2/S2 (INORGANIC) CLUSTER Fe2 S2 NIXDOXVAJZFRNF-UHFFFAOYSA-N |  | ||
| GOL Query on GOL | G [auth B], I [auth C] | GLYCEROL C3 H8 O3 PEDCQBHIVMGVHV-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.66 ?
- R-Value Free: 0.204
- R-Value Work: 0.172
- R-Value Observed: 0.173
- Space Group: P 1 21 1
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 69.483 | ¦Á = 90 |
| b = 226.755 | ¦Â = 108.79 |
| c = 71.425 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| Coot | model building |
| HKL-2000 | data scaling |
| PHASER | phasing |
Entry History & Funding Information
Deposition Data
- Released Date: 2016-02-17 Deposition Author(s): Wu, R., Sanishvili, R., Lee, H.V., Dustin, D.H., Emma, D., Neil, K., Silverman, R.B., Liu, D.
| Funding Organization | Location | Grant Number |
|---|---|---|
| National Institutes of Health/National Cancer Institute (NIH/NCI) | United States | ACB-12002 |
Revision History (Full details and data files)
- Version 1.0: 2016-02-17
Type: Initial release - Version 1.1: 2017-09-20
Changes: Author supporting evidence, Derived calculations, Refinement description - Version 1.2: 2019-12-04
Changes: Author supporting evidence - Version 1.3: 2024-02-28
Changes: Data collection, Database references, Derived calculations
