Download MendeleyCrystal Structure of Galectin-1 in Complex with N-Acetyllactosamine
Grimm, C., Bertleff-Zieschang, N.To be published.
4Q26
Crystal Structure of Galectin-1 in Complex with N-Acetyllactosamine
- PDB DOI: https://doi.org/10.2210/pdb4Q26/pdb
- Classification: SUGAR BINDING PROTEIN
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2014-04-07 Released: 2015-10-07
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.40 ?
- R-Value Free: 0.203
- R-Value Work: 0.162
- R-Value Observed: 0.163
wwPDB Validation 3D Report Full Report
This is version 2.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Galectin-1 | A, B, C [auth G], D [auth H] | 136 | Homo sapiens | Mutation(s): 0 Gene Names: LGALS1 |  |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P09382 (Homo sapiens) Explore P09382 Go to UniProtKB: P09382 | |||||
PHAROS: P09382 GTEx: ENSG00000100097 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P09382 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Oligosaccharides
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| GOL Query on GOL | I [auth G] | GLYCEROL C3 H8 O3 PEDCQBHIVMGVHV-UHFFFAOYSA-N |  | ||
| Modified Residues 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Type | Formula | 2D Diagram | Parent |
| CME Query on CME | A, B, C [auth G], D [auth H] | L-PEPTIDE LINKING | C5 H11 N O3 S2 |  | CYS |
Biologically Interesting Molecules (External Reference) 1 Unique
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| ID | Chains | Name | Type/Class | 2D Diagram | 3D Interactions |
| PRD_900019 Query on PRD_900019 | E [auth C], F [auth D], G [auth E], H [auth F] | N-acetyl-alpha-lactosamine | Oligosaccharide / Glycan component |  | |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.40 ?
- R-Value Free: 0.203
- R-Value Work: 0.162
- R-Value Observed: 0.163
- Space Group: P 21 21 2
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 66.384 | ¦Á = 90 |
| b = 85.517 | ¦Â = 90 |
| c = 116.076 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| PHASER | phasing |
| PHENIX | refinement |
| XDS | data reduction |
| XDS | data scaling |
Entry History
Deposition Data
- Released Date: 2015-10-07 Deposition Author(s): Grimm, C., Bertleff-Zieschang, N.
Revision History (Full details and data files)
- Version 1.0: 2015-10-07
Type: Initial release - Version 2.0: 2020-07-29
Type: Remediation
Reason: Carbohydrate remediation
Changes: Advisory, Atomic model, Data collection, Database references, Derived calculations, Non-polymer description, Structure summary - Version 2.1: 2024-11-06
Changes: Data collection, Database references, Structure summary
