Download MendeleyT. brucei FPPS in complex with CID 126782062
Muenzker, L.To be published.
5QTG
T. brucei FPPS in complex with CID 126782062
- PDB DOI: https://doi.org/10.2210/pdb5QTG/pdb
- Deposition Group: G_1002102 (changed state) ExploreG_1002102
- Classification: Transferase/Transferase inhibitor
- Organism(s): Trypanosoma brucei
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2019-08-09 Released: 2020-10-07
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.09 ?
- R-Value Free: 0.307
- R-Value Work: 0.273
- R-Value Observed: 0.274
This is version 1.1 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Farnesyl pyrophosphate synthase | 369 | Trypanosoma brucei | Mutation(s): 0 |  | |
UniProt | |||||
Find proteins for Q86C09 (Trypanosoma brucei) Explore Q86C09 Go to UniProtKB: Q86C09 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q86C09 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 4 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| PK4 Query on PK4 | B [auth A] | 2-fluoro-N,3-dimethylbenzene-1-sulfonamide C8 H10 F N O2 S PXJRMCHXJXWNJG-UHFFFAOYSA-N |  | ||
| PO4 Query on PO4 | C [auth A], E [auth A] | PHOSPHATE ION O4 P NBIIXXVUZAFLBC-UHFFFAOYSA-K |  | ||
| GOL Query on GOL | F [auth A] | GLYCEROL C3 H8 O3 PEDCQBHIVMGVHV-UHFFFAOYSA-N |  | ||
| NA Query on NA | D [auth A] | SODIUM ION Na FKNQFGJONOIPTF-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.09 ?
- R-Value Free: 0.307
- R-Value Work: 0.273
- R-Value Observed: 0.274
- Space Group: P 61 2 2
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 60.356 | ¦Á = 90 |
| b = 60.356 | ¦Â = 90 |
| c = 344.868 | ¦Ă = 120 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| Aimless | data scaling |
| XDS | data reduction |
| PHASER | phasing |
| PDB_EXTRACT | data extraction |
Entry History
Deposition Data
- Released Date: 2020-10-07 Deposition Author(s): Muenzker, L., Petrick, J.K., Schleberger, C., Cornaciu, I., Marquez, J.A., Jahnke, W.
Revision History (Full details and data files)
- Version 1.0: 2020-10-07
Type: Initial release - Version 1.1: 2024-03-06
Changes: Data collection, Database references
