Download MendeleyXChem group deposition
Raux, B., Krojer, T., von Delft, F., Arrowsmith, C.H., Bountra, C., Edwards, A., Huber, K.V.M.To be published.
5R69
XChem group deposition -- Crystal Structure of human YEATS4 in complex with XS038644e
- PDB DOI: https://doi.org/10.2210/pdb5R69/pdb
- Deposition Group: G_1002134 (changed state) ExploreG_1002134
- Classification: TRANSCRIPTION
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2020-02-29 Released: 2020-12-30
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.83 ?
- R-Value Free: 0.248
- R-Value Work: 0.229
- R-Value Observed: 0.230
This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| YEATS domain-containing protein 4 | A [auth B], B [auth A] | 181 | Homo sapiens | Mutation(s): 0 Gene Names: YEATS4, GAS41 |  |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for O95619 (Homo sapiens) Explore O95619 Go to UniProtKB: O95619 | |||||
PHAROS: O95619 GTEx: ENSG00000127337 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | O95619 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| ZHA (Subject of Investigation/LOI) Query on ZHA | D [auth B], G [auth A] | ~{N}-(5-oxidanylidene-7,8-dihydro-6~{H}-naphthalen-2-yl)ethanamide C12 H13 N O2 WEBCZGJWXXPNHB-UHFFFAOYSA-N |  | ||
| EDO Query on EDO | C [auth B], E [auth A], F [auth A] | 1,2-ETHANEDIOL C2 H6 O2 LYCAIKOWRPUZTN-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.83 ?
- R-Value Free: 0.248
- R-Value Work: 0.229
- R-Value Observed: 0.230
- Space Group: P 1
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 45.6 | ¦Á = 67.58 |
| b = 47.44 | ¦Â = 68.56 |
| c = 58.45 | ¦Ă = 69.02 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| Aimless | data scaling |
| PDB_EXTRACT | data extraction |
| XDS | data reduction |
| REFMAC | phasing |
Entry History
Deposition Data
- Released Date: 2020-12-30 Deposition Author(s): Raux, B., Krojer, T., von Delft, F., Arrowsmith, C.H., Bountra, C., Edwards, A., Huber, K.V.M.
Revision History (Full details and data files)
- Version 1.0: 2020-12-30
Type: Initial release - Version 1.1: 2024-03-06
Changes: Data collection, Database references
