Download MendeleyNON-STEREOSPECIFIC SUBSTRATE CLEAVAGE BY TAGATOSE-BISPHOSPHATE CLASS I ALDOLASE
LowKam, C., Liotard, B., Sygusch, J.To be published.
5F2G
Tagatose-1,6-bisphosphate aldolase from Streptococcus pyogenes Glu164Gln mutant in complex with FBP
- PDB DOI: https://doi.org/10.2210/pdb5F2G/pdb
- Classification: LYASE
- Organism(s): Streptococcus pyogenes serotype M1
- Expression System: Escherichia coli
- Mutation(s): Yes
- Deposited: 2015-12-01 Released: 2016-12-07
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.92 ?
- R-Value Free: 0.196
- R-Value Work: 0.155
- R-Value Observed: 0.156
This is version 1.2 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Tagatose 1,6-diphosphate aldolase 2 | 327 | Streptococcus pyogenes serotype M1 | Mutation(s): 1 Gene Names: lacD2, lacD.2, SPy_1919, M5005_Spy1635 EC: 4.1.2.40 |  | |
UniProt | |||||
Find proteins for P63705 (Streptococcus pyogenes serotype M1) Explore P63705 Go to UniProtKB: P63705 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P63705 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 3 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| P6F Query on P6F | E [auth A] | 1,6-di-O-phosphono-D-fructose C6 H14 O12 P2 XPYBSIWDXQFNMH-UYFOZJQFSA-N |  | ||
| 13P Query on 13P | H [auth B] | 1,3-DIHYDROXYACETONEPHOSPHATE C3 H7 O6 P GNGACRATGGDKBX-UHFFFAOYSA-N |  | ||
| CA Query on CA | F [auth A], G [auth A], I [auth B], J [auth B], K [auth B] | CALCIUM ION Ca BHPQYMZQTOCNFJ-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.92 ?
- R-Value Free: 0.196
- R-Value Work: 0.155
- R-Value Observed: 0.156
- Space Group: P 21 21 21
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 63.712 | ¦Á = 90 |
| b = 106.858 | ¦Â = 90 |
| c = 238.445 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| HKL-2000 | data reduction |
| HKL-2000 | data scaling |
| PHENIX | phasing |
Entry History
Deposition Data
- Released Date: 2016-12-07 Deposition Author(s): LowKam, C.
Revision History (Full details and data files)
- Version 1.0: 2016-12-07
Type: Initial release - Version 1.1: 2017-09-27
Changes: Author supporting evidence - Version 1.2: 2024-11-06
Changes: Data collection, Database references, Derived calculations, Structure summary
