Download MendeleyCOVID-2019 main protease in the apo state
Zhou, X.L., Zhong, F.L., Lin, C., Zhou, H., Hu, X.H., Wang, Q.S., Li, J., Zhang, J.To be published.
7C2Y
The crystal structure of COVID-2019 main protease in the apo state
- PDB DOI: https://doi.org/10.2210/pdb7C2Y/pdb
- Classification: VIRAL PROTEIN
- Organism(s): Severe acute respiratory syndrome coronavirus 2
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2020-05-10 Released: 2020-09-02
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.91 ?
- R-Value Free: 0.262
- R-Value Work: 0.220
- R-Value Observed: 0.222
Starting Model: experimental
View more details
wwPDB Validation 3D Report Full Report
This is version 1.2 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| 3C-like proteinase | 298 | Severe acute respiratory syndrome coronavirus 2 | Mutation(s): 0 Gene Names: rep, 1a-1b EC: 3.4.22.69 |  | |
UniProt | |||||
Find proteins for P0DTD1 (Severe acute respiratory syndrome coronavirus 2) Explore P0DTD1 Go to UniProtKB: P0DTD1 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P0DTD1 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.91 ?
- R-Value Free: 0.262
- R-Value Work: 0.220
- R-Value Observed: 0.222
- Space Group: P 21 21 21
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 67.88 | α = 90 |
| b = 102.34 | β = 90 |
| c = 103.49 | γ = 90 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| XDS | data reduction |
| XDS | data scaling |
| PHENIX | phasing |
Entry History
Deposition Data
- Released Date: 2020-09-02 Deposition Author(s): Zhou, X.L., Zhong, F.L., Lin, C., Zhou, H., Hu, X.H., Wang, Q.S., Li, J., Zhang, J.
Revision History (Full details and data files)
- Version 1.0: 2020-09-02
Type: Initial release - Version 1.1: 2021-03-10
Changes: Structure summary - Version 1.2: 2023-11-29
Changes: Data collection, Database references, Refinement description
