Download MendeleyCrystal Structure of dihydrofolate reductase from Stenotrophomonas maltophilia K279a
Mayclin, S.J., Abendroth, J., Lorimer, D.D., Horanyi, P.S., Edwards, T.E.To be published.
7RZO
Crystal structure of a dihydrofolate reductase (folA) from Stenotrophomonas maltophilia
- PDB DOI: https://doi.org/10.2210/pdb7RZO/pdb
- Classification: OXIDOREDUCTASE
- Organism(s): Stenotrophomonas maltophilia K279a
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2021-08-27 Released: 2021-10-20
- Funding Organization(s): National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.80 ?
- R-Value Free: 0.187
- R-Value Work: 0.157
- R-Value Observed: 0.160
Starting Model: experimental
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wwPDB Validation 3D Report Full Report
This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Dihydrofolate reductase | 171 | Stenotrophomonas maltophilia K279a | Mutation(s): 0 Gene Names: folA, Smlt0814 EC: 1.5.1.3 |  | |
UniProt | |||||
Find proteins for B2FPG1 (Stenotrophomonas maltophilia (strain K279a)) Explore B2FPG1 Go to UniProtKB: B2FPG1 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | B2FPG1 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| EDO Query on EDO | B [auth A], D [auth A] | 1,2-ETHANEDIOL C2 H6 O2 LYCAIKOWRPUZTN-UHFFFAOYSA-N |  | ||
| CL Query on CL | C [auth A] | CHLORIDE ION Cl VEXZGXHMUGYJMC-UHFFFAOYSA-M |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.80 ?
- R-Value Free: 0.187
- R-Value Work: 0.157
- R-Value Observed: 0.160
- Space Group: I 41 2 2
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 104.17 | ¦Á = 90 |
| b = 104.17 | ¦Â = 90 |
| c = 87.64 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| XDS | data reduction |
| XSCALE | data scaling |
| MOLREP | phasing |
| PHENIX | refinement |
| PDB_EXTRACT | data extraction |
Entry History & Funding Information
Deposition Data
- Released Date: 2021-10-20 Deposition Author(s): Seattle Structural Genomics Center for Infectious Disease (SSGCID)
| Funding Organization | Location | Grant Number |
|---|---|---|
| National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID) | United States | -- |
Revision History (Full details and data files)
- Version 1.0: 2021-10-20
Type: Initial release - Version 1.1: 2023-10-18
Changes: Data collection, Refinement description
