Download MendeleyComplex structure of Legionella effector LnaB with host Actin and PR-Ub
Chen, T.T., Ouyang, S.To be published.
8K6E
LnaB-Actin-PRUb ternary complex
- PDB DOI: https://doi.org/10.2210/pdb8K6E/pdb
- Classification: TOXIN
- Organism(s): Oryctolagus cuniculus, Legionella, Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2023-07-25 Released: 2025-02-05
- Funding Organization(s): National Natural Science Foundation of China (NSFC)
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.74 ?
- R-Value Free: 0.245 (Depositor), 0.249 (DCC)
- R-Value Work: 0.188 (Depositor), 0.199 (DCC)
- R-Value Observed: 0.191 (Depositor)
Starting Model: experimental
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This is version 1.0 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Actin gamma 1 | 375 | Oryctolagus cuniculus | Mutation(s): 0 |  | |
UniProt | |||||
Find proteins for A0A8C6VAB1 (Naja naja) Explore A0A8C6VAB1 Go to UniProtKB: A0A8C6VAB1 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | A0A8C6VAB1 | ||||
Sequence AnnotationsExpand | |||||
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Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Legionella effector LnaB | 352 | Legionella | Mutation(s): 0 |  | |
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
Sequence AnnotationsExpand | |||||
| |||||
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 3 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Polyubiquitin-B | 75 | Homo sapiens | Mutation(s): 0 Gene Names: UBB |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for J3QS39 (Homo sapiens) Explore J3QS39 Go to UniProtKB: J3QS39 | |||||
GTEx: ENSG00000170315 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | J3QS39 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| AR6 Query on AR6 | E [auth C] | [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL[HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE C15 H23 N5 O14 P2 SRNWOUGRCWSEMX-ZQSHOCFMSA-N |  | ||
| ANP (Subject of Investigation/LOI) Query on ANP | D [auth A] | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER C10 H17 N6 O12 P3 PVKSNHVPLWYQGJ-KQYNXXCUSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.74 ?
- R-Value Free: 0.245 (Depositor), 0.249 (DCC)
- R-Value Work: 0.188 (Depositor), 0.199 (DCC)
- R-Value Observed: 0.191 (Depositor)
Space Group: P 21 21 2
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 215.317 | ¦Á = 90 |
| b = 55.152 | ¦Â = 90 |
| c = 80.907 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| HKL-2000 | data reduction |
| autoPROC | data scaling |
| PHASER | phasing |
Entry History & Funding Information
Deposition Data
- Released Date: 2025-02-05 Deposition Author(s): Chen, T.T., Ouyang, S.Y.
| Funding Organization | Location | Grant Number |
|---|---|---|
| National Natural Science Foundation of China (NSFC) | China | -- |
Revision History (Full details and data files)
- Version 1.0: 2025-02-05
Type: Initial release
