Download MendeleyEfficient bioamination with an w-transaminase mutant from Aspergillus terreus
He, Y.C.To be published.
8X1F
Crystal structure of an omega-transaminase mutant from Aspergillus terreus with in complex with PLP
- PDB DOI: https://doi.org/10.2210/pdb8X1F/pdb
- Classification: TRANSLOCASE
- Organism(s): Aspergillus terreus NIH2624
- Expression System: Escherichia coli
- Mutation(s): Yes
- Deposited: 2023-11-07 Released: 2023-12-13
- Funding Organization(s): National Natural Science Foundation of China (NSFC)
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.30 ?
- R-Value Free: 0.262
- R-Value Work: 0.221
- R-Value Observed: 0.223
Starting Model: experimental
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This is version 2.0 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| D-aminoacid aminotransferase-like PLP-dependent enzyme | 335 | Aspergillus terreus NIH2624 | Mutation(s): 3 Gene Names: ATEG_10023 |  | |
UniProt | |||||
Find proteins for Q0C8G1 (Aspergillus terreus (strain NIH 2624 / FGSC A1156)) Explore Q0C8G1 Go to UniProtKB: Q0C8G1 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q0C8G1 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| PLP (Subject of Investigation/LOI) Query on PLP | C [auth A], D [auth B] | PYRIDOXAL-5'-PHOSPHATE C8 H10 N O6 P NGVDGCNFYWLIFO-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.30 ?
- R-Value Free: 0.262
- R-Value Work: 0.221
- R-Value Observed: 0.223
- Space Group: I 1 2 1
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 94.436 | ¦Á = 90 |
| b = 113.983 | ¦Â = 91.56 |
| c = 101.424 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| HKL-3000 | data scaling |
| HKL-3000 | data reduction |
| AMPLE | phasing |
| PDB_EXTRACT | data extraction |
Entry History & Funding Information
Deposition Data
| Funding Organization | Location | Grant Number |
|---|---|---|
| National Natural Science Foundation of China (NSFC) | China | 21978072 |
Revision History (Full details and data files)
- Version 1.0: 2023-12-13
Type: Initial release - Version 2.0: 2023-12-20
Changes: Advisory, Atomic model, Database references, Derived calculations, Polymer sequence, Source and taxonomy, Structure summary
