8ZCX | pdb_00008zcx

Crystal Structure of a novel Aldehyde Dehydrogenase from Klebsiella pneumoniae

PDB DOI: https://doi.org/10.2210/pdb8ZCX/pdb

Classification: OXIDOREDUCTASE
Organism(s): Klebsiella pneumoniae
Expression System: Escherichia coli 'BL21-Gold(DE3)pLysS AG
Mutation(s): No

Deposited: 2024-04-30 Released: 2025-05-07
Deposition Author(s): Zhang, J., Han, Y., Liu, W., Zhang, W.
Funding Organization(s): Ministry of Science and Technology (MoST, China)

Experimental Data Snapshot

Method: X-RAY DIFFRACTION
Resolution: 2.44 ?
R-Value Free:
0.252 (Depositor), 0.266 (DCC)
R-Value Work:
0.222 (Depositor), 0.234 (DCC)
R-Value Observed:
0.224 (Depositor)

Starting Model: in silico
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wwPDB Validation 3D Report Full Report

This is version 1.0 of the entry. See complete history.

Literature

Crystal Structure of a novel Aldehyde Dehydrogenase from Klebsiella pneumoniae

Zhang, J., Han, Y., Liu, W., Zhang, W.

To be published.

Macromolecule Content

Total Structure Weight: 210.93 kDa
Atom Count: 14,061
Modelled Residue Count: 1,841
Deposited Residue Count: 1,956
Unique protein chains: 1

Macromolecules

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(by identity cutoff) | 3D Structure

Entity ID: 1
Molecule	Chains	Sequence Length	Organism	Details	Image
Aldehyde dehydrogenase	A, B, C, D	489	Klebsiella pneumoniae	Mutation(s): 0 Gene Names: yfmT, xylC_1, CAZ10_02010, DT376_04100, IPC1295_07430, NCTC13621_03651, PAERUG_P19_London_7_VIM_2_05_10_05035 EC: 1.2.1.3 (PDB Primary Data), 1.2.1.28 (PDB Primary Data)
UniProt
Find proteins for A0A069Q1D5 (Pseudomonas aeruginosa) Explore A0A069Q1D5 Go to UniProtKB: A0A069Q1D5
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	A0A069Q1D5
Sequence Annotations Expand
Reference Sequence

Experimental Data & Validation

Experimental Data

Method: X-RAY DIFFRACTION
Resolution: 2.44 ?
R-Value Free: 0.252 (Depositor), 0.266 (DCC)
R-Value Work: 0.222 (Depositor), 0.234 (DCC)
R-Value Observed: 0.224 (Depositor)

Space Group: P 2₁ 2₁ 2₁

Unit Cell:

Length ( ? )	Angle ( ? )
a = 102.669	α = 90
b = 146.744	β = 90
c = 149.528	γ = 90

Software Package:

Software Name	Purpose
REFMAC	refinement
Aimless	data scaling
HKL-2000	data reduction
PHASER	phasing

Structure Validation

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Entry History & Funding Information

Deposition Data

Released Date: 2025-05-07

Deposition Author(s):

Funding Organization	Location	Grant Number
Ministry of Science and Technology (MoST, China)	China	--

Revision History (Full details and data files)

Version 1.0: 2025-05-07
Type: Initial release

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.