9BX0 | pdb_00009bx0

Structure of influenza A RNP, 4xNP local reconstruction, class 4

PDB DOI: https://doi.org/10.2210/pdb9BX0/pdb
EM Map EMD-44989: EMDB EMDataResource

Classification: VIRAL PROTEIN/RNA
Organism(s): Influenza A virus
Mutation(s): No

Deposited: 2024-05-22 Released: 2025-05-14
Deposition Author(s): Peng, R., Chang, Y.-W.
Funding Organization(s): David and Lucile Packard Foundation

Experimental Data Snapshot

Method: ELECTRON MICROSCOPY
Resolution: 9.20 Å
Aggregation State: PARTICLE
Reconstruction Method: SUBTOMOGRAM AVERAGING

Starting Model: experimental
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wwPDB Validation 3D Report Full Report

This is version 1.0 of the entry. See complete history.

Literature

Molecular basis of influenza ribonucleoprotein complex assembly and processive RNA synthesis

Peng, R., Xu, X., Nepal, B., Gong, Y., Li, F., Ferretti, M.B., Zhou, M., Lynch, K.W., Burslem, G.M., Kortagere, S., Marmorstein, R., Chang, Y.W.

(2025) Science

DOI: https://doi.org/10.1126/science.adq7597

Macromolecule Content

Total Structure Weight: 262.47 kDa
Atom Count: 8,160
Modelled Residue Count: 1,888
Deposited Residue Count: 2,112
Unique protein chains: 1
Unique nucleic acid chains: 1

Macromolecules

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(by identity cutoff) | 3D Structure

Entity ID: 1
Molecule	Chains	Sequence Length	Organism	Details	Image
Nucleoprotein	A, B, C, D	498	Influenza A virus	Mutation(s): 0
UniProt
Find proteins for A0A516TQ93 (Influenza A virus) Explore A0A516TQ93 Go to UniProtKB: A0A516TQ93
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	A0A516TQ93
Sequence Annotations Expand
Reference Sequence

Find similar nucleic acids by:

(by identity cutoff) | 3D Structure

Entity ID: 2
Molecule	Chains	Length	Organism	Image
viral RNA	E, F	60	Influenza A virus
Sequence Annotations Expand
Reference Sequence

Experimental Data & Validation

Experimental Data

Method: ELECTRON MICROSCOPY
Resolution: 9.20 Å
Aggregation State: PARTICLE
Reconstruction Method: SUBTOMOGRAM AVERAGING

EM Software:

Task	Software Package	Version
RECONSTRUCTION	RELION	3.1

Structure Validation

View Full Validation Report

Entry History & Funding Information

Deposition Data

Released Date: 2025-05-14

Deposition Author(s):

Funding Organization	Location	Grant Number
David and Lucile Packard Foundation	United States	2019-69645

Revision History (Full details and data files)

Version 1.0: 2025-05-14
Type: Initial release

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.