Download MendeleyMurine norovirus allosteric escape mutants mimic gut activation.
Smith, T.J.To be published.
9EAP | pdb_00009eap
MNV Allosteric escape mutant V339I + GCDCA
- PDB DOI: https://doi.org/10.2210/pdb9EAP/pdb
- EM Map EMD-47839: EMDB EMDataResource
- Classification: VIRUS
- Organism(s): Murine norovirus 1
- Mutation(s): Yes
- Deposited: 2024-11-11 Released: 2025-05-07
- Funding Organization(s): National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)
Experimental Data Snapshot
- Method: ELECTRON MICROSCOPY
- Resolution: 2.70 Å
- Aggregation State: PARTICLE
- Reconstruction Method: SINGLE PARTICLE
wwPDB Validation 3D Report Full Report
This is version 1.0 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Capsid protein VP1 | 540 | Murine norovirus 1 | Mutation(s): 2 |  | |
UniProt | |||||
Find proteins for Q80J94 (Norovirus (isolate Mouse/NoV/United States/MNV1/2002/GV)) Explore Q80J94 Go to UniProtKB: Q80J94 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q80J94 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| CHO (Subject of Investigation/LOI) Query on CHO | D [auth A], E [auth B], F [auth C] | GLYCOCHENODEOXYCHOLIC ACID C26 H43 N O5 GHCZAUBVMUEKKP-GYPHWSFCSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: ELECTRON MICROSCOPY
- Resolution: 2.70 Å
- Aggregation State: PARTICLE
- Reconstruction Method: SINGLE PARTICLE
| Task | Software Package | Version |
|---|---|---|
| MODEL REFINEMENT | PHENIX | 1.21rc1_5134: |
Entry History & Funding Information
Deposition Data
- Released Date: 2025-05-07 Deposition Author(s): Smith, T.J., Sherman, M.
| Funding Organization | Location | Grant Number |
|---|---|---|
| National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID) | United States | NIH 1R01-AI141465 |
Revision History (Full details and data files)
- Version 1.0: 2025-05-07
Type: Initial release
