Download MendeleyCubic insulin crystal, Esrapid, at pH 2
Ayan, E., Tosha, T.To be published.
9M4X | pdb_00009m4x
Cubic insulin crystal, Esrapid, at pH 2
- PDB DOI: https://doi.org/10.2210/pdb9M4X/pdb
- Classification: HORMONE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2025-03-05 Released: 2025-03-12
- Funding Organization(s): Other government
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.40 ?
- R-Value Free: 0.221 (Depositor), 0.225 (DCC)
- R-Value Work: 0.188 (Depositor), 0.193 (DCC)
- R-Value Observed: 0.191 (Depositor)
Starting Model: experimental
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This is version 1.0 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by: Sequence | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Insulin A chain | 21 | Homo sapiens | Mutation(s): 0 Gene Names: INS |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P01308 (Homo sapiens) Explore P01308 Go to UniProtKB: P01308 | |||||
PHAROS: P01308 GTEx: ENSG00000254647 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P01308 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Insulin B chain | 29 | Homo sapiens | Mutation(s): 0 Gene Names: INS |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P01308 (Homo sapiens) Explore P01308 Go to UniProtKB: P01308 | |||||
PHAROS: P01308 GTEx: ENSG00000254647 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P01308 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| SO4 (Subject of Investigation/LOI) Query on SO4 | C [auth B] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.40 ?
- R-Value Free: 0.221 (Depositor), 0.225 (DCC)
- R-Value Work: 0.188 (Depositor), 0.193 (DCC)
- R-Value Observed: 0.191 (Depositor)
Space Group: I 21 3
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 77.97 | ¦Á = 90 |
| b = 77.97 | ¦Â = 90 |
| c = 77.97 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| HKL-2000 | data reduction |
| HKL-2000 | data scaling |
| PHASER | phasing |
Entry History & Funding Information
Deposition Data
| Funding Organization | Location | Grant Number |
|---|---|---|
| Other government | -- |
Revision History (Full details and data files)
- Version 1.0: 2025-03-12
Type: Initial release
