Download MendeleyStructure of TAB2 NZF domain bound to K6 / Lys6-linked diubiquitin
Michel, M.A., Scutts, S., Komander, D.To be published.
9AVT
Structure of TAB2 NZF domain bound to K6 / Lys6-linked diubiquitin
- PDB DOI: https://doi.org/10.2210/pdb9AVT/pdb
- Classification: SIGNALING PROTEIN
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2024-03-04 Released: 2024-07-31
- Funding Organization(s): Medical Research Council (MRC, United Kingdom), National Health and Medical Research Council (NHMRC, Australia), European Research Council (ERC)
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.50 ?
- R-Value Free: 0.203 (Depositor), 0.200 (DCC)
- R-Value Work: 0.182 (Depositor), 0.180 (DCC)
- R-Value Observed: 0.183 (Depositor)
Starting Model: experimental
View more details
wwPDB Validation 3D Report Full Report
This is version 1.0 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Ubiquitin | 76 | Homo sapiens | Mutation(s): 0 Gene Names: UBB |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P0CG47 (Homo sapiens) Explore P0CG47 Go to UniProtKB: P0CG47 | |||||
PHAROS: P0CG47 GTEx: ENSG00000170315 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P0CG47 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 | 30 | Homo sapiens | Mutation(s): 0 Gene Names: TAB2, KIAA0733, MAP3K7IP2 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q9NYJ8 (Homo sapiens) Explore Q9NYJ8 Go to UniProtKB: Q9NYJ8 | |||||
PHAROS: Q9NYJ8 GTEx: ENSG00000055208 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q9NYJ8 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 3 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| DTT Query on DTT | G [auth B] | 2,3-DIHYDROXY-1,4-DITHIOBUTANE C4 H10 O2 S2 VHJLVAABSRFDPM-IMJSIDKUSA-N |  | ||
| SO4 Query on SO4 | D [auth A], E [auth A], F [auth B], H [auth C] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |  | ||
| ZN Query on ZN | I [auth C] | ZINC ION Zn PTFCDOFLOPIGGS-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.50 ?
- R-Value Free: 0.203 (Depositor), 0.200 (DCC)
- R-Value Work: 0.182 (Depositor), 0.180 (DCC)
- R-Value Observed: 0.183 (Depositor)
Space Group: P 65 2 2
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 90.323 | ¦Á = 90 |
| b = 90.323 | ¦Â = 90 |
| c = 86.335 | ¦Ă = 120 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| Aimless | data scaling |
| XDS | data reduction |
| PHASER | phasing |
Entry History & Funding Information
Deposition Data
- Released Date: 2024-07-31 Deposition Author(s): Michel, M.A., Scutts, S., Komander, D.
| Funding Organization | Location | Grant Number |
|---|---|---|
| Medical Research Council (MRC, United Kingdom) | United Kingdom | U105192732 |
| National Health and Medical Research Council (NHMRC, Australia) | Australia | GNT1178122 |
| European Research Council (ERC) | European Union | 724804 |
Revision History (Full details and data files)
- Version 1.0: 2024-07-31
Type: Initial release
