Download MendeleyX-Ray Structure of Human Phosphomannomutase 2 (PMM2)
Center for Eukaryotic Structural Genomics (CESG)To be published.
2AMY
X-Ray Structure of Human Phosphomannomutase 2 (PMM2)
- PDB DOI: https://doi.org/10.2210/pdb2AMY/pdb
- Classification: ISOMERASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): Yes
- Deposited: 2005-08-10 Released: 2005-08-23
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.09 ?
- R-Value Free: 0.272
- R-Value Work: 0.199
- R-Value Observed: 0.202
wwPDB Validation 3D Report Full Report
This is version 1.4 of the entry. See complete history.
Re-refinement Note
A newer entry is available that reflects an alternative modeling of the original data: 2Q4R
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Phosphomannomutase 2 | 246 | Homo sapiens | Mutation(s): 4 Gene Names: HS.459855 EC: 5.4.2.8 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for O15305 (Homo sapiens) Explore O15305 Go to UniProtKB: O15305 | |||||
PHAROS: O15305 GTEx: ENSG00000140650 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | O15305 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| GLY Query on GLY | C [auth A], D [auth A], E [auth A] | GLYCINE C2 H5 N O2 DHMQDGOQFOQNFH-UHFFFAOYSA-N |  | ||
| EDO Query on EDO | B [auth A] | 1,2-ETHANEDIOL C2 H6 O2 LYCAIKOWRPUZTN-UHFFFAOYSA-N |  | ||
| Modified Residues 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Type | Formula | 2D Diagram | Parent |
| MSE Query on MSE | A | L-PEPTIDE LINKING | C5 H11 N O2 Se |  | MET |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.09 ?
- R-Value Free: 0.272
- R-Value Work: 0.199
- R-Value Observed: 0.202
- Space Group: P 32 2 1
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 70.622 | ¦Á = 90 |
| b = 70.622 | ¦Â = 90 |
| c = 100.15 | ¦Ă = 120 |
| Software Name | Purpose |
|---|---|
| DENZO | data reduction |
| SCALEPACK | data scaling |
| SHARP | phasing |
| DM | phasing |
| REFMAC | refinement |
| PDB_EXTRACT | data extraction |
| SOLOMON | phasing |
| ARP/wARP | model building |
Entry History
Deposition Data
- Released Date: 2005-08-23 Deposition Author(s): Wesenberg, G.E., Phillips Jr., G.N., McCoy, J.G., Bitto, E., Bingman, C.A., Allard, S.T.M., Center for Eukaryotic Structural Genomics (CESG)
Revision History (Full details and data files)
- Version 1.0: 2005-08-23
Type: Initial release - Version 1.1: 2008-04-30
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Advisory, Version format compliance - Version 1.3: 2017-10-11
Changes: Refinement description - Version 1.4: 2018-01-24
Changes: Database references
