Download MendeleyCrystal structure of rituximab
Bzymek, K.P., Williams, J.C.To be published.
4KAQ | pdb_00004kaq
Structure of rituximab Fab
- PDB DOI: https://doi.org/10.2210/pdb4KAQ/pdb
- Classification: IMMUNE SYSTEM
- Organism(s): Homo sapiens, Mus musculus
- Mutation(s): No
- Deposited: 2013-04-22 Released: 2014-12-24
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.48 ?
- R-Value Free: 0.230 (Depositor), 0.230 (DCC)
- R-Value Work: 0.180 (Depositor), 0.180 (DCC)
- R-Value Observed: 0.182 (Depositor)
Starting Model: experimental
View more details
wwPDB Validation 3D Report Full Report
This is version 2.2 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Rituximab light chain | A [auth L] | 213 | Homo sapiens, Mus musculus This entity is chimeric | Mutation(s): 0 |  |
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
Sequence AnnotationsExpand | |||||
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Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Rituximab heavy chain | B [auth H] | 224 | Homo sapiens, Mus musculus This entity is chimeric | Mutation(s): 0 |  |
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Modified Residues 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Type | Formula | 2D Diagram | Parent |
| PCA Query on PCA | B [auth H] | L-PEPTIDE LINKING | C5 H7 N O3 |  | GLN |
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.48 ?
- R-Value Free: 0.230 (Depositor), 0.230 (DCC)
- R-Value Work: 0.180 (Depositor), 0.180 (DCC)
- R-Value Observed: 0.182 (Depositor)
Space Group: C 2 2 21
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 60.65 | ¦Á = 90 |
| b = 93.93 | ¦Â = 90 |
| c = 144.39 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| CrystalClear | data collection |
| PHASER | phasing |
| PHENIX | refinement |
| XDS | data reduction |
| XSCALE | data scaling |
Entry History
Deposition Data
- Released Date: 2014-12-24 Deposition Author(s): Bzymek, K.P., Williams, J.C.
Revision History (Full details and data files)
- Version 1.0: 2014-12-24
Type: Initial release - Version 2.0: 2019-12-25
Changes: Derived calculations, Polymer sequence - Version 2.1: 2023-09-20
Changes: Data collection, Database references, Refinement description - Version 2.2: 2024-10-30
Changes: Structure summary
