Download MendeleyTitle: Structure of the extracellular region of the adhesion GPCR CELSR1 reveals a compact module which regulates G protein-coupling
Bandekar, S.J., Arac, D.To be published.
8VY2 | pdb_00008vy2
Structure of mCELSR1 extracellular region containing CADH9-GAIN domains
- PDB DOI: https://doi.org/10.2210/pdb8VY2/pdb
- EM Map EMD-43644: EMDB EMDataResource
- Classification: SIGNALING PROTEIN
- Organism(s): Mus musculus
- Expression System: Trichoplusia ni
- Mutation(s): No
- Deposited: 2024-02-06 Released: 2025-05-07
- Funding Organization(s): National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)
Experimental Data Snapshot
- Method: ELECTRON MICROSCOPY
- Resolution: 4.30 Å
- Aggregation State: PARTICLE
- Reconstruction Method: SINGLE PARTICLE
wwPDB Validation 3D Report Full Report
This is version 1.0 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Cadherin EGF LAG seven-pass G-type receptor 1 | 2,232 | Mus musculus | Mutation(s): 0 Gene Names: Celsr1 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for O35161 (Mus musculus) Explore O35161 Go to UniProtKB: O35161 | |||||
IMPC: MGI:1100883 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | O35161 | ||||
Glycosylation | |||||
| Glycosylation Sites: 10 | Go to GlyGen: O35161-1 | ||||
Sequence AnnotationsExpand | |||||
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Oligosaccharides
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Length | 2D Diagram | Glycosylation | 3D Interactions |
| 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | B, D, E | 2 |  | N-Glycosylation | |
Entity ID: 3 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Length | 2D Diagram | Glycosylation | 3D Interactions |
| beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | C | 3 |  | N-Glycosylation | |
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| NAG Query on NAG | F [auth A] G [auth A] H [auth A] I [auth A] J [auth A] | 2-acetamido-2-deoxy-beta-D-glucopyranose C8 H15 N O6 OVRNDRQMDRJTHS-FMDGEEDCSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: ELECTRON MICROSCOPY
- Resolution: 4.30 Å
- Aggregation State: PARTICLE
- Reconstruction Method: SINGLE PARTICLE
Entry History & Funding Information
Deposition Data
- Released Date: 2025-05-07 Deposition Author(s): Bandekar, S.J., Arac, D.
| Funding Organization | Location | Grant Number |
|---|---|---|
| National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) | United States | R35GM148412 |
| National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) | United States | F32GM142266 |
Revision History (Full details and data files)
- Version 1.0: 2025-05-07
Type: Initial release
